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The severity of whooping cough in hospitalised children – is it declining?

Published online by Cambridge University Press:  19 October 2009

I. D. A. Johnston ,
H. R. Anderson  and
H. P. Lambert
I. D. A. Johnston
Affiliation:
Department of Clinical Epidemiology and Social Medicine, Department of Communicable Diseases, St George's Hospital Medical School, London, SW17
H. R. Anderson
Affiliation:
Department of Clinical Epidemiology and Social Medicine, Department of Communicable Diseases, St George's Hospital Medical School, London, SW17
H. P. Lambert
Affiliation:
Department of Clinical Epidemiology and Social Medicine, Department of Communicable Diseases, St George's Hospital Medical School, London, SW17
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Summary

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Four hundred and sixty admissions for whooping cough to three hospitals between 1974–9 were reviewed. Many children had a long illness. More than half of them had severe or moderately severe coughing spasms and a quarter had pronounced feeding difficulties. The incidence of clinical pneumonia and convulsions was low and there were no deaths. The disease continues to be much more severe in infancy. There was some evidence that the disease declined in severity over the period studied. A number of factors including increased use of erythromycin may have contributed to this change.

Type
Research Article
Information
Journal of Hygiene , Volume 94 , Issue 2 , April 1985 , pp. 151 - 161
Copyright
Copyright © Cambridge University Press 1985

References

REFERENCES

Baraff, L. J., Wilkins, J. & Wehrle, P. F. (1978). The role of antibiotics, immunisation and adenoviruses in pertussis. Pediatrics 61, 224–230.CrossRefGoogle ScholarPubMed
Barrie, H. (1982). Treatment of whooping cough. Lancet ii, 830–831.CrossRefGoogle Scholar
Bass, J. W., Klenk, E. L., Kotheimer, J. B., Linnemann, C. C., Smith, M. H. D. (1969). Antimicrobial treatment of pertussis. Journal of Pediatrics 75, 768–781.CrossRefGoogle ScholarPubMed
Bassili, W. R. & Stewart, G. T. (1976). Epidemiological evaluation of immunisation and other factors in the control of whooping cough. Lancet i, 471–474.CrossRefGoogle Scholar
Bennett, N. M. (1973). Whooping cough in Melbourne. Medical Journal of Australia 2, 481–487.CrossRefGoogle ScholarPubMed
Christie, A. B. (1980). Infectious Diseases: epidemiology and practice. Edinburgh: Churchill Livingstone.Google Scholar
Church, M. A. (1979). Evidence of whooping cough vaccine efficacy from the 1978 whooping cough epidemic in Hertfordshire. Lancet ii, 188—190.Google Scholar
Court, D., Jackson, H. & Knox, G. (1953). The recognition of whooping cough. Lancet ii, 1057–1060.CrossRefGoogle Scholar
Cvjetanovic, B., Grab, B. & Vemura, K. (1978). Diphtheria and whooping cough. Diseases affecting a particular age group. Bulletin of World Health Organization 56, (Suppl. 1), 103–133.Google Scholar
Demina, A. A., Devyatkina, N. P., Voloshina, L. Z., Larina, L. I., Semina, N. A., Venglinskaya, E. A. & Kostyvkova, K. P. (1973). Serological types of whooping cough bacteria and their connection with immunity in vaccinated children. Journal of Hygiene, Epidemiology, Microbiology and Immunology 17, 304–315.Google ScholarPubMed
Dhss, (Department of Health and Social Security) (1981). Whooping cough: reports from the Committee on Safety of Medicines and the Joint Committee on Vaccination and Immunisation. London: HMSO.Google Scholar
Emerson, H. (1939). Essential problems in pertussis. American Journal of Public Health 29, 337–340.CrossRefGoogle ScholarPubMed
Grob, P. R., Crowder, M. J. & Robbins, J. F. (1981). Effect of vaccination on severity and dissemination of whooping cough. British Medical Journal 282, 1925–1928.CrossRefGoogle ScholarPubMed
Harris, F., Bush, G. & Lewis, M. (1979). Deaths of infants after triple vaccine. Lancet ii, 473.Google Scholar
Islur, J., Anglin, C. S. & Middleton, P. J. (1975). The whooping cough syndrome: a continuing pediatric problem. Clinical Pediatrics 14, 171–176.CrossRefGoogle ScholarPubMed
Jenkinson, D. (1983). Whooping cough: what proportion of cases is notified in an epidemic? British Medical Journal 287, 185–6.CrossRefGoogle Scholar
Jernelius, H. (1958). Pertussis complications and mortality during the period 1934 to 1953. Ada Pediatrica 47, 56–64.CrossRefGoogle ScholarPubMed
Lapin, J. H. (1943). Whooping cough. Springfield Illinois: C. C. Thomas.Google Scholar
Linnemann, C. C. (1979). Host parasite interactions in pertussis. In International symposium on pertussis (ed. Manclark, C. R. & Hill, J. C). DHEW Publication no. (NIH) 79–1830. Washington DC. US Govt. Printing Office.Google Scholar
McKendrick, M. W., Gully, P. R. & Geddes, A. M. (1980). Protection against pertussis by immunisation. British Medical Journal 281, 1390–1391.CrossRefGoogle ScholarPubMed
Melchior, J. C. & Jessen, O. (1976). Experience concerning patients hospitalised with whooping cough during the epidemic in 1973–4. Ugeskrift for Laeger, Copenhagen 138, 1389–1391.Google Scholar
Miller, C. I. & Fletcher, W. B. (1976). The severity of notified whooping cough. British Medical Journal 1, 117–119.CrossRefGoogle ScholarPubMed
Miller, D. L., Ross, E. M., Alderslade, R., Bellman, M. H. & Rawson, N. S. B. (1981). Pertussis immunisation and serious acute neurological illness in childhood. British Medical Journal 282, 1595–1599.CrossRefGoogle Scholar
Miller, D. L., Alderslade, R. & Ross, E. M. (1982). Whooping cough and whooping cough vaccine: the risks and benefits debate. Epidemiologic Reviews 4, 1–24.CrossRefGoogle ScholarPubMed
Miller, E., Jacombs, B. & Pollock, T. M. (1980). Whooping cough notifications. Lancet i, 718.CrossRefGoogle Scholar
Mortimer, E. A. & Jones, P. K. (1979). An evaluation of pertussis vaccine. Reviews of Infectious Diseases 1, 927–932.CrossRefGoogle ScholarPubMed
MRC (Medical Research Council). (1953). Treatment of whooping cough with antibiotics. Lancet, 1109–1112.Google Scholar
Olson, L. C. (1975). Pertussis. Medicine 54, 427–469.CrossRefGoogle ScholarPubMed
Pavesio, D. & Ponzone, A. (1977). Salbutamol and pertussis. Lancet i, 150–151.CrossRefGoogle Scholar
Peltola, H. & Michelsson, K. (1982). Efficacy of salbutamol in treatment of infant pertussis demonstrated by sound spectrum analysis. Lancet i, 310–312.CrossRefGoogle Scholar
PHLS (Report from the PHLS Epidemiological Research Laboratory and 21 Area Health Authorities). (1982). Efficacy of pertussis vaccination in England. British Medical Journal 285, 357–359.Google Scholar
Pollard, R. (1980). Relation between vaccination and notification rates for whooping cough in England and Wales. Lancet i, 1180–1182.CrossRefGoogle Scholar
Pollock, T. M. & Morris, J. (1983). A 7-year survey of disorders attributed to vaccination in North West Thames Region. Lancet i, 753–757.CrossRefGoogle Scholar
Pollock, T. M., Miller, E. & Lobb, J. (1984). Severity of whooping cough in England before and after the decline in pertussis immunisation. Archives of Diseases in Childhood 59, 162–165.CrossRefGoogle ScholarPubMed
Preston, N. W. (1963). Type-specific immunity against whooping cough. British Medical Journal 2, 724–726.CrossRefGoogle ScholarPubMed
RCGP (Report from the Swansea Research Unit of the Royal College of General Practitioners). (1981). Effect of a low pertussis vaccination uptake on a large community. British Medical Journal 282, 23–26.CrossRefGoogle Scholar
Robinson, D. A., Mandal, B. K., Ironside, A. G. & Dunbar, E. M. (1981). Whooping cough – a study of severity in hospitalised cases. Archives of Diseases in Childhood 56, 687–691.CrossRefGoogle Scholar
Trollfors, B. (1979). Clinical course of whooping cough in children younger than 6 months. Acta Pediatrica Scandinavica 68, 323–328.CrossRefGoogle Scholar
Vesselinova-Jenkins, C. K., Newcombe, R. G., Gray, O. P., Skone, J. F., Howells, C. H. L., Lennox, M., Hine, D. J., Jenkins, P. M. & Munro, J. A. (1978). The effects of immunisation upon the natural history of pertussis. A family study in the Cardiff area. Journal of Epidemiology and Community Health 32, 194–199.CrossRefGoogle ScholarPubMed
Voorhoeve, A. M., Muller, A. S., Schulpen, T. W. J., Manetje, W. T. & Vanrens, M. (1978). Machakos Project Studies IV: The Epidemiology of Pertussis. Tropical and Geographical Medicine 30, 125–139.Google ScholarPubMed
Walker, E., Pinkerton, I. W., Love, W. C., Chaudhuri, A. K. R. & Datta, J. B. (1981). Whooping cough in Glasgow 1969–80. Journal of Infection 3, 150–158.CrossRefGoogle ScholarPubMed
Walsh, J. A. & Warren, K. S. (1979). Selective primary health care. An interim strategy for disease control in developing countries. New England Journal of Medicine 301, 967–974.CrossRefGoogle ScholarPubMed
Wynne, J. & Hull, D. (1977). Why are children admitted to hospital? British Medical Journal 2, 1140–1142.CrossRefGoogle ScholarPubMed