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Stool viruses in babies in Glasgow: 1. Hospital admissions with diarrhoea

Published online by Cambridge University Press:  15 May 2009

C. R. Madeley ,
B. P. Cosgrove ,
E. J. Bell  and
R. J. Fallon
C. R. Madeley
Affiliation:
University of GlasgowDepartment of Infectious Diseases
B. P. Cosgrove
Affiliation:
Regional Virus Laboratory
E. J. Bell
Affiliation:
Regional Virus Laboratory
R. J. Fallon
Affiliation:
Department of Laboratory Medicine Ruchill Hospital, Glasgow G 20 9 NB, Scotland
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Summary

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Stools from 183 babies under 2 years of age admitted to Ruchill Hospital with diarrhoea were examined by electron microscopy, virus culture, bacterial culture and light microscopy. As far as possible, several stools were examined from each patient and the results showed rotaviruses, astroviruses and other viruses in association with symptoms, as well as the expected bacterial pathogens. Examination of several stools from the same patient also showed that in this age group the viral flora of the gut changes rapidly and that the viruses seen by electron microscopy were only rarely grown in cell culture and vice versa. This phenomenon was particularly noted with adenoviruses. In 30% of cases no microbial pathogen was identified and in the remainder the presence of the infecting organism did not always coincide with the symptoms. It is concluded that, with viruses at least, presence of the organism does not constitute proof of causation.

Type
Research Article
Information
Journal of Hygiene , Volume 78 , Issue 2 , April 1977 , pp. 261 - 273
Copyright
Copyright © Cambridge University Press 1977

References

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