Published online by Cambridge University Press: 15 May 2009
The inactivation rates of tissue-culture polio virus have been determined and these have been applied to the irradiation of formalinized vaccine, as an additional inactivation process, using a simple irradiator.
The antigenic potency of the vaccine was apparently unimpaired.
We wish to thank the late Prof. van den Ende for his keen interest and criticism; Dr H. Malherbe and his staff for carrying out many of the titrations; Dr P. D. Winter for co-operation in irradiating samples of vaccine, and Margaret Pakes for invaluable technical assistance.