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A study of the specific IgM antibody response in Mycoplasma pneumoniae infection in man

Published online by Cambridge University Press:  15 May 2009

P. Chamberlain  and
A. A. Saeed
P. Chamberlain
Affiliation:
Public Health Laboratory, St Mary's General Hospital, Milton Road, Portsmouth, Hampshire, EnglandPO3 6AQ
A. A. Saeed
Affiliation:
Public Health Laboratory, St Mary's General Hospital, Milton Road, Portsmouth, Hampshire, EnglandPO3 6AQ
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Summary

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Sera from 96 patients with Mycoplasma pneumoniae infection were examined for specific IgM antibody. The complement fixation test was used to measure the IgM after separation by ultracentrifugation through sucrose density gradients. Of patients under the age of 20 years 78 % displayed positive specific IgM titres. In older patients only 34% were IgM positive. The specific IgM remained detectable, but at decreasing levels, during the follow-up period of 5 months. This diagnostic technique appears to be of value in children and young adults experiencing primary infection with M. pneumoniae.

Type
Research Article
Information
Journal of Hygiene , Volume 90 , Issue 2 , April 1983 , pp. 207 - 211
Copyright
Copyright © Cambridge University Press 1983

References

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