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Susceptibility of vitamin A-deficient and starved rats and mice to a peroral infection with Salmonella typhi-murium*

Published online by Cambridge University Press:  15 May 2009

I. J. Kligler ,
K. Guggenheim  and
E. Henig
I. J. Kligler
Affiliation:
Department of Hygiene and Bacteriology, Hebrew University, Jerusalem
K. Guggenheim
Affiliation:
Department of Hygiene and Bacteriology, Hebrew University, Jerusalem
E. Henig
Affiliation:
Department of Hygiene and Bacteriology, Hebrew University, Jerusalem
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Green & Mellanby (1928, 1930) were the first to direct attention to a specific relationship between vitamin A deficiency and infection. They studied the occurrence of spontaneous infections in vitamin A-deficient rats and concluded that animals fed on a diet deficient in vitamin A, but complete in all other respects, develop multiple infective lesions and die. Since then vitamin A has become known as the ‘anti-infective’ vitamin.

Type
Research Article
Information
Journal of Hygiene , Volume 44 , Issue 1 , January 1945 , pp. 61 - 66
Copyright
Copyright © Cambridge University Press 1945

References

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