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Intrathecal sufentanil compared with epidural bupivacaine analgesia in labour

Published online by Cambridge University Press:  16 August 2006

A. Harsten ,
L. Gillberg ,
L. Häkansson  and
M. Olsson
A. Harsten
Affiliation:
Department of Anaesthesiology, Central Hospital, S-291 85 Kristianstad, Sweden
L. Gillberg
Affiliation:
Department of Anaesthesiology, Central Hospital, S-291 85 Kristianstad, Sweden
L. Häkansson
Affiliation:
Department of Anaesthesiology, Central Hospital, S-291 85 Kristianstad, Sweden
M. Olsson
Affiliation:
Department of Gynecology, Central Hospital, S-291 85 Kristianstad, Sweden
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Abstract

Epidural analgesia for pain relief during labour has certain disadvantages including slow onset. However, intrathecal sufentanil provides rapid onset and well-controlled analgesia lasting 1–4 h. The aim of this study was to compare the analgesia and the side effects of intrathecal sufentanil with epidural bupivacaine during labour. In a randomized, double-blind and controlled trial 58 parturient women requesting analgesia during labour were studied. The patients received either intrathecal sufentanil 10 μg and epidural saline, or intrathecal saline and epidural bupivacaine 20 mg. Visual analogue scores (VAS) for pain, blood pressure, heart rate, respiratory rate, level of sedation and the incidence of pruritus and nausea were recorded. Pain scores were significantly lower between 5 and 90 min after injection in patients receiving intrathecal sufentanil. Pruritus was significantly more frequent among those receiving intrathecal sufentanil. The rapid onset and effective analgesia of intrathecal sufentanil may in certain situations be advantageous.

Keywords

anaesthesiaobstetricanalgesicsopioidsufentanilanaestheticslocalbupivacaineanaesthetic techniquesepiduralintrathecal
Type
Original Article
Information
European Journal of Anaesthesiology , Volume 14 , Issue 6 , November 1997 , pp. 642 - 645
Copyright
1997 European Society of Anaesthesiology

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