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Post-operative pain relief in children following extraction of carious deciduous teeth under general anaesthesia: a comparison of nalbuphine and diclofenac

Published online by Cambridge University Press:  04 August 2006

I. H. Littlejohn ,
M. M. Tarling ,
P. J. Flynn ,
A. J. Ordman  and
A. Aiken
I. H. Littlejohn
Affiliation:
Anaesthetics Unit, The London Hospital Medical College, Royal London Hospital, Whitechapel, London, UK
M. M. Tarling
Affiliation:
Anaesthetics Unit, The London Hospital Medical College, Royal London Hospital, Whitechapel, London, UK
P. J. Flynn
Affiliation:
Anaesthetics Unit, The London Hospital Medical College, Royal London Hospital, Whitechapel, London, UK
A. J. Ordman
Affiliation:
Anaesthetics Unit, The London Hospital Medical College, Royal London Hospital, Whitechapel, London, UK
A. Aiken
Affiliation:
Anaesthetics Unit, The London Hospital Medical College, Royal London Hospital, Whitechapel, London, UK
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Abstract

In a randomized double-blind study 60 children, undergoing the extraction of carious deciduous teeth under day-case general anaesthesia, were assigned to receive either intravenous nalbuphine hydrochloride 0.3 mg kg−1 (n = 21), one or more diclofenac suppositories 12.5 mg to a dose of 1–2 mg kg−1 (n = 19), or no analgesia (n = 20). The duration of anaesthesia was longer in the diclofenac group (9.6 min, SD 3.5) compared with control (7.2 min, SD 2.6) and nalbuphine (6.9 min, SD 3.0) groups respectively (P < 0.05). There were no statistically significant differences in post-operative pain scores during the 45 min post-operative period studied between the three groups using an objective pain score. We conclude that using this methodology we were unable to demonstrate any statistically significant differences between the analgesic effects of either intravenous (i.v.) nalbuphine or diclofenac suppositories compared with control.

Keywords

analgesicsdiclofenacnalbuphineanalgesiapost-operativepaediatric
Type
Original Article
Information
European Journal of Anaesthesiology , Volume 13 , Issue 4 , April 1996 , pp. 359 - 363
Copyright
1996 European Society of Anaesthesiology

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