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Effect of caudal block on the plasma adrenaline and noradrenaline concentrations in paediatric patients undergoing ilioinguinal herniorrhaphy

Published online by Cambridge University Press:  16 August 2006

Luis A. Gaitini ,
Mostafa Somri ,
Sonia J. Vaida ,
Milo Fradis ,
Edmond Sabo ,
Jorge Mogilner ,
Nurit Levy ,
Avital Greenberg ,
Sofia Lischinsky  and
Oren Zinder
Luis A. Gaitini
Affiliation:
Department of Anaesthesia, Bnai-Zion Medical Centre, 47 Golomb Street, PO Box 4940, 31048 Haifa, Israel
Mostafa Somri
Affiliation:
Department of Anaesthesia, Bnai-Zion Medical Centre, 47 Golomb Street, PO Box 4940, 31048 Haifa, Israel
Sonia J. Vaida
Affiliation:
Department of Anaesthesia, Bnai-Zion Medical Centre, 47 Golomb Street, PO Box 4940, 31048 Haifa, Israel
Milo Fradis
Affiliation:
Department of Anaesthesia, Bnai-Zion Medical Centre, 47 Golomb Street, PO Box 4940, 31048 Haifa, Israel
Edmond Sabo
Affiliation:
Department of Anaesthesia, Bnai-Zion Medical Centre, 47 Golomb Street, PO Box 4940, 31048 Haifa, Israel
Jorge Mogilner
Affiliation:
Paediatric Surgery Department, Bnai-Zion Medical Centre, 47 Golomb Street, PO Box 4940, 31048 Haifa, Israel
Nurit Levy
Affiliation:
Department of Clinical Biochemistry, Rambam Medical Centre, Haifa, Israel
Avital Greenberg
Affiliation:
Department of Clinical Biochemistry, Rambam Medical Centre, Haifa, Israel
Sofia Lischinsky
Affiliation:
Department of Clinical Biochemistry, Rambam Medical Centre, Haifa, Israel
Oren Zinder
Affiliation:
Department of Clinical Biochemistry, Rambam Medical Centre, Haifa, Israel
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Abstract

This study compared the effect of two anaesthetic techniques on the catecholamine levels in children undergoing ilioinguinal herniorrhaphy. Forty male paediatric patients ASA class I were allocated randomly to one of two groups: the control group (n=20) received general anaesthesia including intravenous fentanyl; and the caudal group (n=20) received caudal anaesthesia with bupivacaine 0.25% 1mL kg−1; combined with general anaesthesia but without opioids. Plasma adrenaline and noradrenaline concentrations were measured at induction, at the end of surgery and in the post-anaesthesia care unit (PACU). In the caudal group, there were significant decreases in the adrenaline and noradrenaline concentrations at the end of surgery and in the PACU compared with baseline concentrations. In the control group, there was a significant increase in PACU concentrations of adrenaline and noradrenaline compared with baseline concentrations. These findings suggest that the addition of a caudal block to general anaesthesia in children undergoing ilioinguinal herniorrhaphy decreases significantly the neurohormonal responses to surgery.

Keywords

catecholaminesadrenalinenoradrenalinestress responsepaediatric anaesthesiacaudal anaesthesia
Type
Original Article
Information
European Journal of Anaesthesiology , Volume 16 , Issue 2 , February 1999 , pp. 92 - 97
Copyright
1999 European Society of Anaesthesiology

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