Hostname: page-component-78c5997874-s2hrs Total loading time: 0 Render date: 2024-11-10T08:06:39.406Z Has data issue: false hasContentIssue false

Nutrition support and treatment of motility disorders in critically ill patients – Results of a survey on German intensive care units

Published online by Cambridge University Press:  01 January 2008

K. D. Röhm*
Affiliation:
Klinikum Ludwigshafen, Department of Anaesthesiology and Intensive Care Medicine, Bremserstrasse, Ludwigshafen, Germany
T. Schöllhorn
Affiliation:
Klinikum Ludwigshafen, Department of Anaesthesiology and Intensive Care Medicine, Bremserstrasse, Ludwigshafen, Germany
J. Boldt
Affiliation:
Klinikum Ludwigshafen, Department of Anaesthesiology and Intensive Care Medicine, Bremserstrasse, Ludwigshafen, Germany
M. Wolf
Affiliation:
Klinikum Ludwigshafen, Department of Anaesthesiology and Intensive Care Medicine, Bremserstrasse, Ludwigshafen, Germany
M. Papsdorf
Affiliation:
Klinikum Ludwigshafen, Department of Anaesthesiology and Intensive Care Medicine, Bremserstrasse, Ludwigshafen, Germany
S. N. Piper
Affiliation:
Klinikum Ludwigshafen, Department of Anaesthesiology and Intensive Care Medicine, Bremserstrasse, Ludwigshafen, Germany
*
Correspondence to: Kerstin D. Röhm, Department of Anaesthesiology and Intensive Care Medicine, Klinikum Ludwigshafen, Bremserstrasse 79, D-67063 Ludwigshafen, Germany. E-mail: k.d.roehm@web.de; Tel: +49 621 503 3000; Fax: +49 621 503 3024
Get access

Summary

Background and objective

To evaluate the current clinical attitude in enteral nutrition support and motility disorders in adult critically ill patients on German intensive care units.

Methods

A total of 1493 questionnaires, including 25 items on the medical environment, treatment of motility disorders and enteral nutrition, were sent to German intensive care units in September 2005. Responses were collected during a 2-month period.

Results

A total of 593 questionnaires were returned (response rate 41%). The intensive care units were mainly led by anaesthesiologists (63%) or internists (17%). Standard nutrition protocols were used in 44%. Feeding was mainly started as a combined enteral–parenteral regimen (70%). Early enteral nutrition was performed in 58% using a volume of 250–500 mL (66%) and increased by 200–400 mL day−1 (55%). It was mainly delivered by gastric tube (76%) via continuous pump systems (72%) with short interruption intervals of <4 h (86%). Enteral nutrition solutions were mainly standard polymeric formulae (86%). Modified solutions for diabetics and those with renal or liver failure were uncommonly used; immunonutrition did not play a role. Prokinetic agents, especially metoclopramide, laxatives and neostigmine, were routinely used (39%). Further therapeutic options in motility dysfunction included purgative enemas (96%), gastrografin (72%) and colon massage (39%).

Conclusions

The concept of early enteral nutrition has been well established and approved in German intensive care units, though the recommendations only meet level C criteria in the current ESPEN guidelines. The current survey may serve for further updates on practical nutrition support in intensive care medicine.

Type
Original Article
Copyright
Copyright © European Society of Anaesthesiology 2007

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

Part of this data was presented as a poster at the DIVI Congress (German Interdisciplinary Association of Critical Care Medicine), November 2006, Hamburg, Germany.

References

1.Landow, L, Andersen, LW. Splanchnic ischaemia and its role in multiple organ failure. Acta Anaesthesiol Scand 1994; 38 (7): 626639.CrossRefGoogle ScholarPubMed
2.Kompan, L, Kremzar, B, Gadzijev, E, Prosek, M. Effects of early enteral nutrition on intestinal permeability and the development of multiple organ failure after multiple injury. Intensive Care Med 1999; 25 (2): 157161.CrossRefGoogle ScholarPubMed
3.Mentec, H, Dupont, H, Bocchetti, M, Cani, P, Ponche, F, Bleichner, G. Upper digestive intolerance during enteral nutrition in critically ill patients: frequency, risk factors, and complications. Crit Care Med 2001; 29 (10): 19551961.CrossRefGoogle ScholarPubMed
4.Martin, CM, Doig, GS, Heyland, DK, Morrison, T, Sibbald, WJ. Multicentre, cluster-randomized clinical trial of algorithms for critical-care enteral and parenteral therapy (ACCEPT). CMAJ 2004; 170 (2): 197204.Google ScholarPubMed
5.Lewis, SJ, Egger, M, Sylvester, PA, Thomas, S. Early enteral feeding versus ‘nil by mouth’ after gastrointestinal surgery: systematic review and meta-analysis of controlled trials. BMJ 2001; 323 (7316): 773776.CrossRefGoogle ScholarPubMed
6.Heyland, DK. Nutritional support in the critically ill patients. A critical review of the evidence. Crit Care Clin 1998; 14 (3): 423440.CrossRefGoogle ScholarPubMed
7.Heyland, DK, Dhaliwal, R, Drover, JW, Gramlich, L, Dodek, P. Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN J Parenter Enteral Nutr 2003; 27 (5): 355373.CrossRefGoogle ScholarPubMed
8.ASPEN Board of Directors and the Clinical Guidelines Task Force. Guidelines for the use of parenteral and enteral nutrition in adult and pediatric patients. JPEN J Parenter Enteral Nutr 2002; 26 (Suppl 1): 1SA138SA.Google Scholar
9.Kreymann, KG, Berger, MM, Deutz, NE et al. . ESPEN guidelines on enteral nutrition: intensive care. Clin Nutr 2006; 25 (2): 210223.CrossRefGoogle ScholarPubMed
10. Adressbuch DK. Rembach, Druck- und Verlagshaus GmbH & CoKG. Unterwerkstrasse 5, D-79115 Freiburg/Germany 2004.Google Scholar
11.Gianotti, L, Alexander, JW, Nelson, JL, Fukushima, R, Pyles, T, Chalk, CL. Role of early enteral feeding and acute starvation on postburn bacterial translocation and host defense: prospective, randomized trials. Crit Care Med 1994; 22 (2): 265272.CrossRefGoogle ScholarPubMed
12.Chiarelli, A, Enzi, G, Casadei, A, Baggio, B, Valerio, A, Mazzoleni, F. Very early nutrition supplementation in burned patients. Am J Clin Nutr 1990; 51 (6): 10351039.CrossRefGoogle ScholarPubMed
13.Kreymann, G, Ebener, C, Hartl, W, von Heymann, C, Spiess, C. DGEM guidelines enteral nutrition: intensive care. Aktuel Ernaehr Med 2003; 28 (Suppl 1): S42S50.CrossRefGoogle Scholar
14.Marik, PE, Zaloga, GP. Early enteral nutrition in acutely ill patients: a systematic review. Crit Care Med 2001; 29 (12): 22642270.CrossRefGoogle ScholarPubMed
15.Preiser, JC, Berré, J, Carpentier, Y et al. . Management of nutrition in European intensive care units: results of a questionnaire. Intensive Care Med 1999; 25: 95101.CrossRefGoogle ScholarPubMed
16.Barr, J, Hecht, M, Flavin, KE, Khorana, A, Gould, MK. Outcomes in critically ill patients before and after the implementation of an evidence-based nutritional management protocol. Chest 2004; 125 (4): 14461457.CrossRefGoogle ScholarPubMed
17.Mackenzie, SL, Zygun, DA, Whitmore, BL, Doig, CJ, Hameed, SM. Implementation of a nutrition support protocol increases the proportion of mechanically ventilated patients reaching enteral nutrition targets in the adult intensive care unit. JPEN J Parenter Enteral Nutr 2005; 29 (2): 7480.CrossRefGoogle ScholarPubMed
18.Cerra, FB, Benitez, MR, Blackburn, GL et al. . Applied nutrition in ICU patients. A consensus statement of the American College of Chest Physicians. Chest 1997; 111 (3): 769778.CrossRefGoogle ScholarPubMed
19.Weimann, A, Jauch, KW, Kemen, M et al. . DGEM-leitlinie enterale ernährung: chirurgie und transplantation. Akt Ernaehr Med 2003; 28 (Suppl): S51.CrossRefGoogle Scholar
20.Stroud, M, Duncan, H, Nightingale, J. Guidelines for enteral feeding in adult hospital patients. Gut 2003; 52 (Suppl 7): vii1vii12.CrossRefGoogle ScholarPubMed
21.Heyland, DK, Novak, F, Drover, JW, Jain, M, Su, X, Suchner, U. Should immunonutrition become routine in critically ill patients? A systematic review of the evidence. JAMA 2001; 286 (8): 944953.CrossRefGoogle ScholarPubMed
22.Lovat, R, Preiser, JC. Antioxidant therapy in intensive care. Curr Opin Crit Care 2003; 9 (4): 266270.CrossRefGoogle ScholarPubMed
23.Heyland, DK, Dhaliwal, R, Suchner, U, Berger, MM. Antioxidant nutrients: a systematic review of trace elements and vitamins in the critically ill patient. Intensive Care Med 2005; 31 (3): 327337.CrossRefGoogle ScholarPubMed
24.Crimi, E, Liguori, A, Condorelli, M et al. . The beneficial effects of antioxidant supplementation in enteral feeding in critically ill patients: a prospective, randomized, double-blind, placebo-controlled trial. Anesth Analg 2004; 99 (3): 857863, Table of contents.CrossRefGoogle ScholarPubMed
25.Dive, A, Foret, F, Jamart, J, Bulpa, P, Installe, E. Effect of dopamine on gastrointestinal motility during critical illness. Intensive Care Med 2000; 26 (7): 901907.CrossRefGoogle ScholarPubMed
26.Booth, CM, Heyland, DK, Paterson, WG. Gastrointestinal promotility drugs in the critical care setting: a systematic review of the evidence. Crit Care Med 2002; 30 (7): 14291435.CrossRefGoogle ScholarPubMed
27.MacLaren, R, Patrick, WD, Hall, RI, Rocker, GM, Whelan, GJ, Lima, JJ. Comparison of cisapride and metoclopramide for facilitating gastric emptying and improving tolerance to intragastric enteral nutrition in critically ill, mechanically ventilated adults. Clin Ther 2001; 23 (11): 18551866.CrossRefGoogle Scholar
28.Chapman, MJ, Fraser, RJ, Kluger, MT, Buist, MD, De Nichilo, DJ. Erythromycin improves gastric emptying in critically ill patients intolerant of nasogastric feeding. Crit Care Med 2000; 28 (7): 23342337.CrossRefGoogle ScholarPubMed
29.van der Spoel, JI, Oudemans-van Straaten, HM, Stoutenbeek, CP, Bosman, RJ, Zandstra, DF. Neostigmine resolves critical illness-related colonic ileus in intensive care patients with multiple organ failure – a prospective, double-blind, placebo-controlled trial. Intensive Care Med 2001; 27 (5): 822827.CrossRefGoogle ScholarPubMed
30.Layton, D, Key, C, Shakir, SA. Prolongation of the QT interval and cardiac arrhythmias associated with cisapride: limitations of the pharmacoepidemiological studies conducted and proposals for the future. Pharmacoepidemiol Drug Saf 2003; 12 (1): 3140.CrossRefGoogle Scholar
31.Steinbrook, RA. Epidural anesthesia and gastrointestinal motility. Anesth Analg 1998; 86 (4): 837844.Google ScholarPubMed