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Calidad de vida y costes de tratamiento en pacientes ambulatorios esquizofrénicos tratados con neurolépticos depot

Published online by Cambridge University Press:  12 May 2020

M.Z. Dernovsek
Affiliation:
Hospital Psiquiátrico Universitario, Studenec 48, SI-1260Ljubljana-Polje, Eslovenia;
V. Prevolnik Rupel
Affiliation:
Ministerio de Salud, Stefanova 5, SI-1000Ljubjana, Eslovenia;
M. Rebolj
Affiliation:
Escuela de Economía, Kardaljeva ploscad 17, SI-1000Ljubljana, Eslovenia
R. Tavcar
Affiliation:
Hospital Psiquiátrico Universitario, Studenec 48, SI-1260Ljubljana-Polje, Eslovenia;
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Resumen

El propósito del estudio era 1) descubrir las influencias en la calidad de vida (CDV) de los pacientes ambulatorios crónicos con esquizofrenia, 2) calcular los años de vida ajustados según la calidad (AVAC), y 3) estimar los costes directos de un año de tratamiento. En una muestra del 20% (100 varones, 100 mujeres) de los pacientes ambulatorios esquizofrénicos de la Clínica Ambulatoria en Ljubljana, Eslovenia, que recibían neurolépticos depot, se recogieron los datos demográficos, clínicos y de tratamiento para el año 1996. Se utilizó la Escala de Krawiecka, la Escala de Evaluación Global (GAS), la Escala de Movimientos Involuntarios Anormales, la Escala de Evaluación para la Acatisia Inducida por los Medicamentos, la Escala de Evaluación para los Efectos Secundarios Extrapiramidales, la Escala de Calidad de Vida (QLS), la EQ-5D y los AVAC. Se utilizó regresión lineal multivariable con la puntuación de la QLS como variable dependiente. Los pacientes tenían 44 años de media y habían recibido tratamiento durante 14 años. La puntuación media de la GAS era 70. La GAS se relacionaba positivamente con la puntuación de la QLS, mientras que la puntuación de parkinsonismo estaba correlacionada inversamente con la QLS. Los pacientes pueden esperar vivir 10,20 más AVAC como media. La CDV en la escala EQ-5D era 0,73. Los costes directos del tratamiento anual ascendían a 216,216$ en precios de 1996. En pacientes crónicos bien ajustados con esquizofrenia, la CDV parece depender sobre todo de su rendimiento psicosocial y los efectos secundarios. Aunque infrecuentes, las nuevas hospitalizaciones explicaban la mitad de todos los gastos de tratamiento.

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References

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