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Combinación de nefazodona y midazolam durante terapia electroconvulsiva

Published online by Cambridge University Press:  12 May 2020

A. Conca ,
Z. Al-Dubai ,
P. König  and
W. Beraus
A. Conca
Affiliation:
Departamento de Psiquiatría I, Hospital Regional Rankweil, Rankweil, Austria
Z. Al-Dubai
Affiliation:
Departamento de Psiquiatría I, Hospital Regional Rankweil, Rankweil, Austria
P. König
Affiliation:
Departamento de Psiquiatría I, Hospital Regional Rankweil, Rankweil, Austria
W. Beraus
Affiliation:
Departamento de Psiquiatría I, Hospital Regional Rankweil, Rankweil, Austria
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Resumen

Comunicamos el caso de un paciente que sufría distimia. Fue sometido a un tratamiento de ECT con éxito y fue medicado con nefazodona y midazolam. Comparando el EEG y la duración de la crisis motora en los periodos con y sin midazolam, no se registraron diferencias significativas, pero las dosis de tiopental y de succinilcolina se tuvieron que aumentar de manera notable después de la interrupción del midazolam (P < 0,05; ANOVA). Este caso indica una interacción farmacodinámica sustancial entre nefazodona, midazolam, tiopental y succinilcolina.

Keywords

TECmidazolamnefazodona
Type
Informe Clínico
Information
European Psychiatry (Ed. Española) , Volume 7 , Issue 5 , June 2000 , pp. 314 - 317
Copyright
Copyright © European Psychiatric Association 2000

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References

Bibliografía

American Psychiatric Association. The practice of ECT: recommendations for treatment, training, and privileging. Task force report on ECT. Washington, DC: American Psychiatric Press; 1990.Google Scholar
Coffey, CELucke, JWeiner, RDKrystal, ADAque, M.Seizure threshold in electroconvulsive therapy: I. Initial seizure threshold. Biol Psychiatry 1995;37:713–20.CrossRefGoogle ScholarPubMed
Gassy, JERay, JM.A survey of ECT in a general hospital psychiatric unit. Aust NZ J Psychiatry 1990;24:385–90.CrossRefGoogle Scholar
Greenberg, RMPettinati, HM.Benzodiazepine and electroconvulsive therapy. Convulsive Ther 1993;9:262–73.Google ScholarPubMed
Kellner, CHBourgon, LN.Combining ECT and antide-pressants: time to reassess. J Ect 1998;14:65–7.CrossRefGoogle Scholar
Linder, MWRussell, APrough, AValdes, R.Jr. Pharmacogenetics: a laboratory tool for optimizing thera-peutic efficiency. Clin Chem 1997;43:254–66.CrossRefGoogle Scholar
Nemeroff, CBdeVane, CLPollock, BG.Newer antide-pressants and the cytochrome P450 System. Am J Psychiatry 1996;28:241–7.Google Scholar
Pritchett, JTBernstein, JHKellner, CH.Combinded ECT and antidepressant drug therapy. Convulsive Ther 1993;9:256–61.Google Scholar
Sackeim, HA.Optimizing unilateral electroconvulsive therapy. Convulsive Ther 1991;7:201–12.Google ScholarPubMed
Selvin, BL.Electroconvulsive therapy-1987. Anesthesiology 1987;67:367–85.CrossRefGoogle ScholarPubMed