Hostname: page-component-78c5997874-j824f Total loading time: 0 Render date: 2024-11-10T17:15:44.375Z Has data issue: false hasContentIssue false

Efectos subjetivos de la MDMA (“éxtasis”) sobre la función sexual humana

Published online by Cambridge University Press:  12 May 2020

Z. Zemishlany
Affiliation:
Hospital Psiquiatrico Geha, Petah Tikva y Facultad Sackler de Medicina, Universidad de Tel Aviv, P. O. Box 102, Petah Tikva49100, Israel
D. Aizenberg
Affiliation:
Hospital Psiquiatrico Geha, Petah Tikva y Facultad Sackler de Medicina, Universidad de Tel Aviv, P. O. Box 102, Petah Tikva49100, Israel
A. Weizman
Affiliation:
Hospital Psiquiatrico Geha, Petah Tikva y Facultad Sackler de Medicina, Universidad de Tel Aviv, P. O. Box 102, Petah Tikva49100, Israel
Get access

Resumen

Se evaluó subjetivamente la función sexual después del consumo de 3,4-metilenodioximetanfetamina (MDMA a “éxtasis”) en 35 usuarios recreativos sanos (20 hombres y 15 mujeres, 21-48 años de edad) con respecto a cuatro dominios importantes de la actividad sexual: el deseo, la erección (la lubricación en las mujeres), el orgasmo y la satisfacción. El MDMA aumentó de moderada a profundamente el deseo y la satisfacción en más del 90% de los sujetos. El orgasmo se retrasó, pero se percibió como más intenso. La erección estaba disminuida en el 40% de los hombres. Parece que el MDMA deteriora la ejecución sexual, a pesar del aumento del deseo sexual y la as percepción de mayor satisfacción.

Type
Comunicación breve
Copyright
Copyright © European Psychiatric Association 2001

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bibliografía

Argiolas, A, Melis, MR. Neuromodulation of penile erection: an overview of the role of neurotransmitters and neuropeptides. Prog Neurobiol 1995; 47: 235–55.10.1016/0301-0082(95)80003-QCrossRefGoogle ScholarPubMed
Bowers, MB Jr, Morton, JB. Regional brain catecholamines and metabolites following THC, PCP and MK-801. Prog Neuropsychopharmacol Biol Psychiatry 1994; 18: 961–4.10.1016/0278-5846(94)90111-2CrossRefGoogle ScholarPubMed
Buffum, J, Moser, C. MDMA and human sexual function. J Psychoactive Drugs 1986; 18: 355–9.10.1080/02791072.1986.10472369CrossRefGoogle ScholarPubMed
Cohen, RS. Subjective reports on the effects of the MDMA ("Ecstasy") experience in humans. Prog Neuropsychopharmacol Biol Psychiatry 1995; 19: 1137–45.10.1016/0278-5846(95)00231-6CrossRefGoogle ScholarPubMed
Cohen, RS. The love drug: marching to the beat of ecstasy. Binghampton, NY: The Haworth Medical Press; 1998.Google Scholar
Kaplan, HS. The sexual desire disorder: dysfunctional regulation of sexual motivation. New York: Brunner/ Mazel, 1995.Google Scholar
Koch, S, Galloway, MP. MDMA induced dopamine ralease in vivo: role of endogenous serotonin. J Neural Transm 1997; 104: 135–46.10.1007/BF01273176CrossRefGoogle ScholarPubMed
Malatesta, V, Pollack, R, Crotty, T, Peacock, L. Acute alcohol intoxication and female orgasmic response. J Sex Res 1982; 18: 117.10.1080/00224498209551130CrossRefGoogle Scholar
Pfaus, JG, Everitt, BJ. The psychopharmacology of sexual behavior. In: Bloom, FE, KupLer, DJ, Eds. Psychopharmacology: the fourth generation of progress. New York: Raven Press; 1995. p. 743-58.Google Scholar
Randall, T. Ecstasy-fueled "rave" parties become dances of death for English youths. JAMA 1992, 268: 1505–6.10.1001/jama.268.12.1505CrossRefGoogle ScholarPubMed
Rosen, RS, Lane, RM, Menza, M. Effects of SSRIs on sexual function: a critical review. J Clin Psychopharmacol 1999; 19: 6785.10.1097/00004714-199902000-00013CrossRefGoogle ScholarPubMed
Schiavi, RC, Segraves, RT. The biology of sexual function. Psychiatr Clin North Am 1995; 18: 723.10.1016/S0193-953X(18)30067-4CrossRefGoogle ScholarPubMed
Segraves, RT. Antidepressant-induced sexual dysfunction. J Clin Psychiatry 1998; 59 (Suppl 4): 4854.Google ScholarPubMed
Shankaran, M, Gudelsky, GA. Effect of 3,4 - methylene-dioxymethamphetamine (MDMA) on hippocampal dopamine and serotonin. Pharmacol Biochem Behav 1998; 61: 361–6.10.1016/S0091-3057(98)00103-8CrossRefGoogle ScholarPubMed
Steele, TD, McCann, UD, Ricaurte, GA. 3,4 - methylene-dioxymethamphetamine (MDMA, "Ecstasy"): pharmacology and toxicology in animals and humans. Addiction 1994; 89: 539–51.10.1111/j.1360-0443.1994.tb03330.xCrossRefGoogle ScholarPubMed
Valevski, A, Modai, I, Zbarski, E, Zemishlany, Z, Weizman, A. Effects of amantadine on sexual function in neurolep-tic-treated male schizophrenic patients. Clin Neurophar-macol 1998; 21: 355–7.Google ScholarPubMed
Wilson, GT, Lawson, DM. The effects of alcohol on sexual arousal in women. J Abnorm Psychol 1976; 85: 489–97.10.1037/0021-843X.85.5.489CrossRefGoogle ScholarPubMed
Wolff, K, Hay, AWM, Sherlock, K, Conner, M. Contents of "ecstasy" [letter]. Lancet 1995; 346: 1100–1.10.1016/S0140-6736(95)91774-8CrossRefGoogle Scholar