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Función hemisférica en la esquizofrenia de tipo desorganizado: rendimiento en la prueba de extinción de cualidades

Published online by Cambridge University Press:  12 May 2020

B. Spivak ,
D. Elimelech ,
R. Ocring ,
R. Mester ,
M. Kotler  and
A. Weizman
B. Spivak
Affiliation:
Unidad de Investigatión, Centro de Salud de Ness Ziona, Ness Ziona, Israel Facultad Sackler de Medicina, Universidad de Tel Aviv, Tel Aviv, Israel
D. Elimelech
Affiliation:
Unidad de Investigatión, Centro de Salud de Ness Ziona, Ness Ziona, Israel
R. Ocring
Affiliation:
Unidad de Investigatión, Hospital Psiquiátrico Geha y Laboratorio de Psiquiatría Biológica, Centro de Investigatión Médica Felsenstein, Petah Tikva, Israel
R. Mester
Affiliation:
Unidad de Investigatión, Centro de Salud de Ness Ziona, Ness Ziona, Israel Facultad Sackler de Medicina, Universidad de Tel Aviv, Tel Aviv, Israel
M. Kotler
Affiliation:
Facultad de Medicina, Universidad Ben-Gurion, Beer-Sheva, Israel
A. Weizman
Affiliation:
Facultad Sackler de Medicina, Universidad de Tel Aviv, Tel Aviv, Israel Unidad de Investigatión, Hospital Psiquiátrico Geha y Laboratorio de Psiquiatría Biológica, Centro de Investigatión Médica Felsenstein, Petah Tikva, Israel
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Resumen

Evaluamos la función hemisféca en pacientes varones diestros con esquizofrenia crónica de tipo desorganizado (n = 60, intervalo de edad de 18-45 años) utilizando la prueba de extinción de cualidades (PEC), en comparación con 20 controles varones sanos y diestros en el mismo intervalo de edad. El análisis de la PEC discriminó entre los pacientes con esquizofrenia desorganizada y los controles. Los resultados de la prueba indicaban que los pacientes con esquizofrenia crónica eran menos sensibles a los estímulos táctiles en ambas manos en comparación con los controles. Ademá la sensibilidad a los estímulos táctiles en la mano izquierda era menor que en la mano derecha en los pacientes esquizofrénicos. Por contraste, en los controles normales la sensibilidad era similar en ambas manos. Estos resultados indican una posible disfunción del hemisferio derecho junto con una perturbación en la transmisión interhemisférica a través del cuerpo calloso en los pacientes con esquizofrenia crónica de tipo desorganizado.

Keywords

esquizofrenia crónicacuerpo callosohemisferiosprueba de extinción de cualidades
Type
Artículo original
Information
European Psychiatry (Ed. Española) , Volume 8 , Issue 1 , February 2001 , pp. 20 - 26

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References

Bibliografía

Andreasen, NCDennert, JWOlsen, SADamasio, ARHemispheric asymmetries and schizophrenia. Am J Psychiatry 1982; 139: 427–30.Google Scholar
Beaumont, JGDimond, SJBrain disconnection and schizophrenia. Br J Psychiatry 1973; 123: 661–2.CrossRefGoogle Scholar
Bigelow, LBNasrallah, HARausher, FPCorpus callosum thickness in chronic schizophrenia. Br J Psychiatry 1983; 142: 284–7.CrossRefGoogle ScholarPubMed
Bruder, GECerebral laterality and psychopathology: a review of dichotic listening studies. Schizophr Bull 1983; 9: 134–51.CrossRefGoogle ScholarPubMed
Buchsbaum, MSSomeya, TYing, Teng CAbel, LChin, SNajafi, Aet al. PET and MRI of the thalamus in never-medicated patients with schizophrenia. Am J Psychiatry 1996; 153: 191–9.Google ScholarPubMed
Coren, SPorac, CDuncan, PA behaviorally validated self-report inventory to assess four types of lateral preference. J Clin Neuropsychol 1979; 1: 55–64.CrossRefGoogle Scholar
Cutting, JThe role of right hemisphere dysfunction in psychiatric disorders. Br J Psychiatry 1992; 160: 583–8.CrossRefGoogle ScholarPubMed
Golden, CJGraber, BCoffman, JBerg, RANewlin, DBBloch, S.Structural brain deficits in shcizophrenia. Arch Gen Psychiatry 1981; 38: 1014–7.CrossRefGoogle Scholar
Gruzelier, JHemispheric imbalances masquerading as paranoid and nonparanoid syndromes. Schizophr Bull 1981; 7: 662–73.CrossRefGoogle Scholar
Gruzelier, JHCerebral laterality and psychopathology: fact and fiction. Psychol Med 1981; 11: 219–27.Google ScholarPubMed
Gur, RECognitive concomitants of hemispheric dysfunction in schizophrenia. Arch Gen Psychiatry 1979; 36: 269–74.CrossRefGoogle Scholar
Karny, NNachshon, IAbnormal lateralization in schizophrenia: empirical evidence for an integrated model. Eur Psychiatry 1995; 10: 75–84.CrossRefGoogle ScholarPubMed
Lerner, JNachshon, ICannon, AResponse of paranoid and nonparanoid schizophrenics in a dichotic listening task. J Nerv Ment Dis 1977; 164: 247–52.CrossRefGoogle Scholar
Lishman, WAToone, BKColbourn, CJMcMeekan, ERLMance, RMDichotic listening in psychotic patients. Br J Psychiatry 1978; 132: 333–41.CrossRefGoogle ScholarPubMed
Magaro, PAPage, JBrain disconnection, schizophrenia and paranoia. J Nerv Ment Dis 1983; 171: 133–40.CrossRefGoogle ScholarPubMed
Marin, RSTucker, GJPsychopathology and hemispheric dysfunction: a review. J Nerv Ment Dis 1981; 169: 546–57.CrossRefGoogle ScholarPubMed
Merrin, ELSchizophrenia and brain asymmetry: an evaluation of evidence for dominant lobe dysfunction. J Nerv Ment Dis 1981; 169: 405–16.CrossRefGoogle ScholarPubMed
Nachshon, IHemispheric dysfunction in schizophrenia. J Nerv Ment Dis 1980; 168: 241–2.CrossRefGoogle Scholar
Nachshon, IDichotic listening models of cerebral deficits in schizophrenia. In: Hugdahl, K Ed. Handbook of dichotic listening: theory, methods and research. Sussex, England: Wiley; 1988. p. 565–94.Google Scholar
Nasrallah, HAMcCalley-Whitters, MKuperman, SNeurological differences between paranoid and nonparanoid schizophrenia: part I. Sensory-motor lateralization. J Clin Psychiatry 1982; 43: 305–6.Google ScholarPubMed
Nasrallah, HARizzo, MDamasio, HMcCalley-Whitters, MKuperman, SJacoby, CGNeurological differences between paranoid and nonparanoid schizophrenia: part II. Computerized tomographic findings. J Clin Psychiatry 1982; 43: 307–9.Google ScholarPubMed
Nasrallah, HATippin, JMcCalley-Whitters, MKuperman, SNeurological differences between paranoid and nonparanoid schizophrenia: part III. Neurological soft signs. J Clin Psychiatry 1982; 43: 310–2.Google ScholarPubMed
Nasrallah, HAMcCalley-Whitters, MBigelow, LBRausher, AHistological strudy of the corpus callosum in chronic schizophrenia. Psychiatr Res 1983; 8: 251–60.CrossRefGoogle Scholar
Scarone, SGaravaglia, PFCazzullo, CLFurther evidence of dominant hemispheric dysfunction in chronic schizophrenia. Br J Psychiatry 1982; 138: 354–5.CrossRefGoogle Scholar
Scarone, SPieri, EGambini, OMassironi, RCazzullo, CLThe asymmetric lateralization of tactile extinction and schizophrenia: the possible role of limbic and frontal regions. Br J Psychiatry 1982; 141: 350–3.CrossRefGoogle ScholarPubMed
Scarone, SCazzullo, CLGambini, OAsymmetry of late-ralised hemispheric function in schizophrenia: influence of clinical and epidemiological characteristics on quality extinction test performance. Br J Psychiatry 1987; 151: 15–7.CrossRefGoogle ScholarPubMed
Schwartz, ASMarchok, PLFlynn, REA sensitive test for tactile extinction: results in patients with parietal and frontal lobe disease. J Neurol Neurosurg Psychiatry 1977; 40: 228–33.CrossRefGoogle ScholarPubMed
Schwartz, ASMarchok, PLKreinick, CJFlynn, REThe asymmetric lateralization of tactile extinction in patients with unilateral cerebral dysfunction. Brain 1979; 102: 669–84.CrossRefGoogle ScholarPubMed
Schweitzer, ]LBecker, EWelsh, HAbnormalities of cerebral lateralization in schizophrenia patients. Arch Gen Psychiatry 1978; 35: 982–5.CrossRefGoogle ScholarPubMed
Spivak, BKarny, NKatz, GRadwan, MApter, AMester, RWeizman, A.Functional hemisphere imbalance in patients with paranoid or disorganized schizophrenia. Eur Psychiatry 1996; 11: 175–9.CrossRefGoogle ScholarPubMed
Voeller, KKSClinical neurologic aspects of the right-hemisphere deficit syndrome. J Child Neurol 1995; 10: 16–22.CrossRefGoogle ScholarPubMed
Walker, EHoppes, EEmory, EA reinterpretation of findings on hemispheric dysfunction in schizophrenia. J Nerv Ment Dis 1981; 169: 378–80.CrossRefGoogle Scholar
Wexler, BECerebral laterality and psychiatry: a review of the literature. Am J Psychiatry 1980; 137: 279–91.Google ScholarPubMed