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Bradykinesia In Patients With Obsessive-Compulsive Disorder

Published online by Cambridge University Press:  16 April 2020

M. Pasquini ,
G. Fabbrini ,
G. Moretti ,
I. Berardelli ,
G. Mandarelli ,
R. Delle Chiaie ,
C. Leone ,
M. Biondi  and
A. Berardelli
M. Pasquini
Affiliation:
Department of Psychiatric Sciences and Psychological Medicine, Sapienza University of Rome, Rome, Italy
G. Fabbrini
Affiliation:
Department of Neurological Sciences, Sapienza University of Rome, Neuromed Institute, Viale dell’Università 30, 00185Rome, Italy
G. Moretti
Affiliation:
Department of Psychiatric Sciences and Psychological Medicine, Sapienza University of Rome, Rome, Italy
I. Berardelli
Affiliation:
Department of Psychiatric Sciences and Psychological Medicine, Sapienza University of Rome, Rome, Italy
G. Mandarelli
Affiliation:
Department of Psychiatric Sciences and Psychological Medicine, Sapienza University of Rome, Rome, Italy
R. Delle Chiaie
Affiliation:
Department of Psychiatric Sciences and Psychological Medicine, Sapienza University of Rome, Rome, Italy
C. Leone
Affiliation:
Department of Psychiatric Sciences and Psychological Medicine, Sapienza University of Rome, Rome, Italy
M. Biondi
Affiliation:
Department of Psychiatric Sciences and Psychological Medicine, Sapienza University of Rome, Rome, Italy
A. Berardelli*
Affiliation:
Department of Neurological Sciences, Sapienza University of Rome, Neuromed Institute, Viale dell’Università 30, 00185Rome, Italy
*
*Corresponding author. Tel.: +39 0649914700; fax: +39 0649914700. E-mail address: alfredo.berardelli@uniroma1.it (A. Berardelli).
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Abstract

Objective

To investigate the frequency of bradykinesia in patients with obsessive-compulsive disorder (OCD) and to see whether patients with OCD who also have bradykinesia display distinctive neuropsychological and neuropsychiatric features.

Methods

We studied 23 antipsychotic-free patients with OCD and 13 healthy controls. Bradykinesia was assessed with section III of the Unified Parkinson Disease Rating Scale. The Wechsler Adult Intelligent Scales-Revised (WAIS-R) was used to assess the Full Scale IQ and to measure visuospatial, visuoconstructional ability and psychomotor speed/mental slowness.

Results

Of the 23 patients with OCD studied, 8 (34%) had mild symptoms of bradykinesia. No relationship was found between bradykinesia and the sociodemographic variables assessed but this motor symptom was significantly associated with the severity of compulsions. Patients with bradykinesia differed from those without: they had a higher frequency of repeating compulsions, and lower IQ scores, performance scores, and WAIS-R subtest scores for similarities and picture completion. No significant differences were found between patients without bradykinesia and healthy controls in any test.

Conclusions

Clinical assessment of motor symptoms in adult patients with OCD often discloses mild bradykinesia sometimes associated with repeating compulsions and poor WAIS-R performance scores.

Keywords

Obsessive-compulsive disorderBradykinesiaBasal ganglia
Type
Obsessive-Compulsive Disorders
Information
European Psychiatry , Volume 25 , Issue 7 , November 2010 , pp. 378 - 381
Copyright
Copyright © Elsevier Masson SAS 2019

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