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Clonidine test and MMPI scales in major depression: state or trait markers ?

Published online by Cambridge University Press:  16 April 2020

M Hansenne ,
W Pitchot ,
A Gonzalez Moreno ,
R von Frenckell  and
M Ansseau
M Hansenne
Affiliation:
Psychiatric Unit, Centre Hospitalier Universitaire du Sart-Tilman, B 35, B-4000Liège, Belgium
W Pitchot
Affiliation:
Psychiatric Unit, Centre Hospitalier Universitaire du Sart-Tilman, B 35, B-4000Liège, Belgium
A Gonzalez Moreno
Affiliation:
Psychiatric Unit, Centre Hospitalier Universitaire du Sart-Tilman, B 35, B-4000Liège, Belgium
R von Frenckell
Affiliation:
Psychiatric Unit, Centre Hospitalier Universitaire du Sart-Tilman, B 35, B-4000Liège, Belgium
M Ansseau
Affiliation:
Psychiatric Unit, Centre Hospitalier Universitaire du Sart-Tilman, B 35, B-4000Liège, Belgium
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Summary

The relationship between growth hormone (GH) response to clonidine and the Minnesota Multiphasic Personality Inventory (MMPI) was assessed in 20 major depressive inpatients. GH response to clonidine was negatively correlated with the depression, the psychasthenia as well as the social introversion MMPI scale scores, and positively correlated with the hypomania scale scores. In contrast, the Carroll depression scale did not exhibit any relationship with either GH response to clonidine or MMPI depression scale. These findings support the role of the clonidine test and several MMPI scales as trait markers for depressive illness.

Keywords

MMPIclonidine testmajor depressionCarroll depression scale
Type
Original article
Information
European Psychiatry , Volume 7 , Issue 3 , 1992 , pp. 129 - 133
Copyright
Copyright © Elsevier, Paris 1992

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