Hostname: page-component-745bb68f8f-kw2vx Total loading time: 0 Render date: 2025-02-04T01:41:18.800Z Has data issue: false hasContentIssue false
  • English
  • Français

Mindfulness-based cognitive therapy for bipolar disorder: A feasibility trial

Published online by Cambridge University Press:  16 April 2020

B. Weber ,
F. Jermann ,
M. Gex-Fabry ,
A. Nallet ,
G. Bondolfi  and
J.-M. Aubry
B. Weber
Affiliation:
Geneva University Hospital, Department of Psychiatry, Bipolar Program, 6-8, rue du 31-Décembre, 1207Geneva, Switzerland
F. Jermann
Affiliation:
Geneva University Hospital, Department of Psychiatry, Depression Program, 6-8, rue du 31-Décembre, 1207Geneva, Switzerland
M. Gex-Fabry
Affiliation:
Geneva University Hospital, Department of Psychiatry, Division of Adult Psychiatry, 2, chemin du Petit-Bel-Air, 1224Chêne-Bourg, Switzerland
A. Nallet
Affiliation:
Geneva University Hospital, Department of Psychiatry, Bipolar Program, 6-8, rue du 31-Décembre, 1207Geneva, Switzerland
G. Bondolfi
Affiliation:
Geneva University Hospital, Department of Psychiatry, Depression Program, 6-8, rue du 31-Décembre, 1207Geneva, Switzerland
J.-M. Aubry*
Affiliation:
Geneva University Hospital, Department of Psychiatry, Bipolar Program, 6-8, rue du 31-Décembre, 1207Geneva, Switzerland
*
*Corresponding author. Tel.: +00 41 22 718 45 38. E-mail address: jean-michel.aubry@hcuge.ch (J.-M. Aubry).
Get access

Abstract

Background

The present open study investigates the feasibility of Mindfulness-based cognitive therapy (MBCT) in groups solely composed of bipolar patients of various subtypes. MBCT has been mostly evaluated with remitted unipolar depressed patients and little is known about this treatment in bipolar disorder.

Methods

Bipolar outpatients (type I, II and NOS) were included and evaluated for depressive and hypomanic symptoms, as well as mindfulness skills before and after MBCT. Patients’ expectations before the program, perceived benefit after completion and frequency of mindfulness practice were also recorded.

Results

Of 23 included patients, 15 attended at least four MBCT sessions. Most participants reported having durably, moderately to very much benefited from the program, although mindfulness practice decreased over time. Whereas no significant increase of mindfulness skills was detected during the trial, change of mindfulness skills was significantly associated with change of depressive symptoms between pre- and post-MBCT assessments.

Conclusions

MBCT is feasible and well perceived among bipolar patients. Larger and randomized controlled studies are required to further evaluate its efficacy, in particular regarding depressive and (hypo)manic relapse prevention. The mediating role of mindfulness on clinical outcome needs further examination and efforts should be provided to enhance the persistence of meditation practice with time.

Keywords

Cognitive therapyMindfulnessBipolar disordersOutpatients
Type
Bipolar Disorder
Information
European Psychiatry , Volume 25 , Issue 6 , October 2010 , pp. 334 - 337
Copyright
Copyright © Elsevier Masson SAS 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baer, RA, Smith, GT, Allen, KBAssessment of mindfulness by self-report: the Kentucky inventory of mindfulness skills. Assessment 2004;11:191–206.CrossRefGoogle ScholarPubMed
Baer, RA, Smith, GT, Hopkins, J, Krietemeyer, J, Toney, LUsing self-report assessment methods to explore facets of mindfulness. Assessment 2006;13:27–45.CrossRefGoogle ScholarPubMed
Beck, AT, Steer, RA, Ball, R, Ranieri, WComparison of Beck Depression Inventories -IA and -II in psychiatric outpatients. J Pers Assess 1996;67:588–597.CrossRefGoogle ScholarPubMed
Bondolfi, G, Jermann, F, der Linden, MV, Gex-Fabry, M, Bizzini, L, Rouget, BW, et al.Depression relapse prophylaxis with Mindfulness-based cognitive therapy: replication and extension in the Swiss health care system. J Affect Disord 2010;122:224–31.CrossRefGoogle ScholarPubMed
Carmody, J, Baer, RARelationships between mindfulness practice and levels of mindfulness, medical and psychological symptoms and well-being in a mindfulness-based stress reduction program. J Behav Med 2008;31:23–33.CrossRefGoogle Scholar
Davidson, RJ, Kabat-Zinn, J, Schumacher, J, Rosenkranz, M, Muller, D, Santorelli, SFet al.Alterations in brain and immune function produced by mindfulness meditation. Psychosom Med 2003;65:564–570.CrossRefGoogle ScholarPubMed
Eisendrath, SJ, Delucchi, K, Bitner, R, Fenimore, P, Smit, M, McLane, MMindfulness-based cognitive therapy for treatment-resistant depression: a pilot study. Psychother Psychosom 2008;77:319–320.CrossRefGoogle ScholarPubMed
Favre, S, Aubry, JM, Gex-Fabry, M, Ragama-Pardos, E, McQuillan, A, Bertschy, GTraduction et validation française de l’échelle de manie de Young (YMRS). Encephale 2003;29:499–505.Google Scholar
Finucane, A, Mercer, SWAn exploratory mixed methods study of the acceptability and effectiveness of Mindfulness-based cognitive therapy for patients with active depression and anxiety in primary care. BMC Psychiatry 2006;6:14.CrossRefGoogle ScholarPubMed
Kenny, MA, Williams, JMGTreatment-resistant depressed patients show a good response to Mindfulness-based cognitive therapy. Behav Res Ther 2007;45:617–625.CrossRefGoogle ScholarPubMed
Kingston, T, Dooley, B, Bates, A, Lawlor, E, Malone, KMindfulness-based cognitive therapy for residual depressive symptoms. Psychol Psychother 2007;80:193–203.CrossRefGoogle ScholarPubMed
Kuyken, W, Byford, S, Taylor, RS, Watkins, E, Holden, E, White, Ket al.Mindfulness-based cognitive therapy to prevent relapse in recurrent depression. J Consult Clin Psychol 2008;76:966–978.CrossRefGoogle ScholarPubMed
Lam, D, Jones, S, Bright, J, Hayward, PCognitive therapy for bipolar disorder: a therapist's guide to concepts, methods and practice. Chichester, NY: John Wiley; 1999.Google Scholar
Ma, S, Teasdale, JDMindfulness-based cognitive therapy for depression: replication and exploration of differential relapse prevention effects. J Consult Clin Psychol 2004;72:31–40.CrossRefGoogle ScholarPubMed
Miklowitz, DJ, Alatiq, Y, Goodwin, GM, Geddes, JR, Fennell, MJ, Dimidjian, Set al.A pilot study of mindfulness-based cognitive therapy for bipolar disorder. Int J Cogn Ther 2009;2:373–382.CrossRefGoogle Scholar
Mirabel-Sarron, C, Siobud Dorocant, E, Sala, L, Bachelart, M, Guelfi, JD, Rouillon, FMindfulness-based cognitive therapy (MBCT) dans la prévention des rechutes thymiques chez le patient bipolaire I : une étude pilote. Ann Med Psychol 2009;167:686–692.Google Scholar
Montgomery, SA, Asberg, MA new depression scale designed to be sensitive to change. Br J Psychiatry 1979;134:382–389.CrossRefGoogle ScholarPubMed
Nicastro, R, Jermann, F, Bondolfi, G, McQuillan, AAssessment of mindfulness with the French version of the Kentucky Inventory of Mindfulness Skills in community and borderline personality disorder samples. Assessment 2010. doi:10.1177/1073191110363551.CrossRefGoogle Scholar
Segal, ZV, Williams, JMG, Teasdale, JDMindfulness-based cognitive therapy for depression: a new approach to preventing relapse. New York: Guilford Press; 2002.Google Scholar
Segal, ZV, Williams, JMG, Teasdale, JDLa thérapie cognitive basée sur la pleine conscience pour la dépression : une nouvelle approche pour prévenir la rechute. Bruxelles: De Boeck; 2006.Google Scholar
Teasdale, JD, Segal, ZV, Williams, JMG, Ridgeway, VA, Soulsby, JM, Lau, MAPrevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. J Consult Clin Psychol 2000;68:615–623.CrossRefGoogle ScholarPubMed
Walach, H, Buchheld, N, Buttenmüller, V, Kleinknecht, N, Schmidt, SMeasuring mindfulness--the Freiburg Mindfulness Inventory (FMI). Pers Individ Dif 2006;40:1543–1555.CrossRefGoogle Scholar
Williams, JM, Alatiq, Y, Crane, C, Barnhofer, T, Fennell, MJ, Duggan, DSet al.Mindfulness-based cognitive therapy (MBCT) in bipolar disorder: preliminary evaluation of immediate effects on between-episode functioning. J Affect Disord 2008;107:275–279.CrossRefGoogle ScholarPubMed
Young, RC, Biggs, JT, Ziegler, VE, Meyer, DAA rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry 1978;133:429–435.CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.