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Sustained antipsychotic effect of metacognitive training in psychosis: A randomized-controlled study

Published online by Cambridge University Press:  15 April 2020

J. Favrod ,
S. Rexhaj ,
S. Bardy ,
P. Ferrari ,
C. Hayoz ,
S. Moritz ,
P. Conus  and
C. Bonsack
J. Favrod*
Affiliation:
La Source, School of Nursing Sciences, University of Applied Sciences of Western Switzerland, avenue Vinet 30, 1004Lausanne, Switzerland Community Psychiatry Service, Department of psychiatry, University Hospital Center of Lausanne, site de Cery, 1008Prilly, Switzerland
S. Rexhaj
Affiliation:
La Source, School of Nursing Sciences, University of Applied Sciences of Western Switzerland, avenue Vinet 30, 1004Lausanne, Switzerland Community Psychiatry Service, Department of psychiatry, University Hospital Center of Lausanne, site de Cery, 1008Prilly, Switzerland
S. Bardy
Affiliation:
Community Psychiatry Service, Department of psychiatry, University Hospital Center of Lausanne, site de Cery, 1008Prilly, Switzerland
P. Ferrari
Affiliation:
La Source, School of Nursing Sciences, University of Applied Sciences of Western Switzerland, avenue Vinet 30, 1004Lausanne, Switzerland Community Psychiatry Service, Department of psychiatry, University Hospital Center of Lausanne, site de Cery, 1008Prilly, Switzerland
C. Hayoz
Affiliation:
HorizonSud, case postale 41, 1633Marsens, Switzerland
S. Moritz
Affiliation:
Department of Psychiatry and Psychotherapy, University Medical Center in Hamburg-Eppendorf, Martinistraße 52, 20246Hamburg, Germany
P. Conus
Affiliation:
General Psychiatry Service, Department of psychiatry, University Hospital Center of Lausanne, site de Cery, 1008Prilly, Switzerland
C. Bonsack
Affiliation:
Community Psychiatry Service, Department of psychiatry, University Hospital Center of Lausanne, site de Cery, 1008Prilly, Switzerland
*
*Corresponding author. Tel.: +41 79 447 31 57. E-mail addresses:j.favrod@ecolelasource.ch (J. Favrod).
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Abstract

Persistent psychotic symptoms represent a major challenge for psychiatric care. Basic research has shown that psychotic symptoms are associated with cognitive biases. Metacognitive training (MCT) aims at helping patients to become aware of these biases and to improve problem-solving. Fifty-two participants fulfilling diagnostic criteria of schizophrenia or schizoaffective disorders and persistent delusions and stabilized antipsychotic medication were enrolled in this study. Following baseline assessment patients were randomized either to treatment as usual (TAU) conditions or TAU + MCT. The intervention consisted of eight weekly 1-hour sessions (maximum: 8 hours). Participants were assessed at 8 weeks and 6-months later by blind assessors. Participants were assessed with the Psychotic Symptoms Rating Scales (PSYRATS) and the positive subscale of the PANSS. Between-group differences in post- and pre-test values were significant at a medium effect size in favor of the MCT for the PSYRATS delusion scale and the positive scale of the PANSS both at post and follow-up. The results of this study indicate that MCT training has a surplus antipsychotic effect for patients suffering from schizophrenia-related disorders who demonstrate only a partial response to antipsychotic treatment and that the effect of the intervention persists for at least 6 months after the intervention.

Keywords

PsychosisSchizophreniaCognitive biasesRandomized studyMetacognitive training
Type
Original articles
Information
European Psychiatry , Volume 29 , Issue 5 , June 2014 , pp. 275 - 281
Copyright
Copyright © Elsevier Masson SAS 2014

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Footnotes

1

Equal contributors.

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