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Amisulpride in dysthymia: results of a naturalistic study in general practice

Published online by Cambridge University Press:  16 April 2020

M Paes de Sousa*
Affiliation:
Department of Psychiatry, Hospital de Santa Maria, Av Egas Moniz 1600 Lisbon, Portuga
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Summary

A naturalistic study was conducted in general practice in Portugal on the efficacy and tolerance of low doses of amisulpride in the treatment of dysthymia. A total of 109 patients received low doses (50 – 100 mg) of amisulpride for four weeks. A global evaluation showed good or very good efficacy and tolerance in more than 80% of the patients. The social disability observed at baseline was significantly improved after the four-week treatment period. Few adverse events were observed and only four patients dropped out due to side effects. Our results suggest that low doses of amisulpride might be a safe and effective treatment for dysthymia in clinical practice.

Type
Research Article
Copyright
Copyright © Elsevier paris 1996

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