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Bipolar mania with psychosis vs without psychosis: A clinical characterization with indirect measures of severity

Published online by Cambridge University Press:  13 August 2021

F. Andrade ,
A.S. Machado ,
A. Vieira  and
A. Silva
F. Andrade*
Affiliation:
Psychiatry Clinic, Centro Hospitalar e Universitário de São João, Porto, Portugal
A.S. Machado
Affiliation:
Psychiatry Clinic, Centro Hospitalar e Universitário de São João, Porto, Portugal
A. Vieira
Affiliation:
Psychiatry Clinic, Centro Hospitalar e Universitário de São João, Porto, Portugal
A. Silva
Affiliation:
Psychiatry Clinic, Centro Hospitalar e Universitário de São João, Porto, Portugal
*
*Corresponding author.

Abstract

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Introduction

The presence of psychotic symptoms is highest during acute episodes of bipolar mania. There is no evidence base regarding the implications of psychosis in the prognosis of bipolar disorder, despite common assumption that their occurrence reflects greater disease severity.

Objectives

We aim to compare sociodemographic and clinical characteristics of inpatients admitted for bipolar mania with and without psychotic features.

Methods

Retrospective observational study of inpatients admitted between January 1st 2017 and 31 October 2020 in a psychiatry inpatient unit of a tertiary hospital. Descriptive analysis of the results was performed using the SPSS software, version 26.0.

Results

Between 2017 and October 2020 there were 103 admissions due to mania bipolar I disorder, 53.4% (n=55) with psychotic symptoms. When compared with mania without psychosis, psychotic mania was associated to male gender (71.1% to 39.7%; c2(1, N = 103) = 10,06; p = 0.02) and younger age (t(103) = -2.43; p = 0.017). The proportion of compulsory admissions and average length of stay were similar between mania with psychosis and mania without psychosis. Also, having a manic bipolar episode with psychotic symptoms was not associated to being prescribed a long-acting injectable antipsychotic.

Conclusions

The presence of psychotic symptoms in bipolar manic episodes were associated to male gender and younger age but not to indirect measures of illness severity.

Disclosure

No significant relationships.

Keywords

bipolar disordermaníapsychotic simptomsseverity
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S82 - S83
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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