Hostname: page-component-cd9895bd7-mkpzs Total loading time: 0 Render date: 2024-12-25T18:11:35.308Z Has data issue: false hasContentIssue false
  • English
  • Français

Childhood psychopathological antecedents in early onset schizophrenia

Published online by Cambridge University Press:  16 April 2020

F. Muratori ,
F. Salvadori ,
G. D’Arcangelo ,
V. Viglione  and
L Picchi
F. Muratori*
Affiliation:
University of Pisa, Pisa, Italy
F. Salvadori
Affiliation:
Division of Child Neuropsichiatry, Scientific Institute Stella Maris, Calambrone, Pisa, Italy
G. D’Arcangelo
Affiliation:
Division of Child Neuropsichiatry, Scientific Institute Stella Maris, Calambrone, Pisa, Italy
V. Viglione
Affiliation:
Division of Child Neuropsichiatry, Scientific Institute Stella Maris, Calambrone, Pisa, Italy
L Picchi
Affiliation:
Division of Child Neuropsichiatry, Scientific Institute Stella Maris, Calambrone, Pisa, Italy
*
*Corresponding author. Present address: c/o IRCCS Stella Maris, Via dei Giacinti, 2, 56018 Calambrone, Pisa, Italy. Tel.: +39 050 886 292; fax: +39 050 886 247. E-mail address: f.muratori@inpe.unipi.it (F. Muratori).
Get access

Abstract

Objective

To describe the premorbid state of early onset schizophrenia (EOS).

Methods

Twenty-three adolescents with EOS were compared to a healthy control group (CG) and to a group of anorexic patients (AG). The premorbid state was studied through the CBCL and the data obtained were analyzed using ANOVA’s and t-test.

Results

During the premorbid period EOS showed significantly higher scores on all scales, relative to the CG, and only on some scales (social, thought and attention problems, and school competencies) relative to the AG.

Conclusions

Children who develop first episode psychosis during adolescence differ from children with normal development. The premorbid internalizing state is common to AG but social competencies and school problems are the most affected areas in EOS when compared to the AG. It is hypothesized that both EOS and AG can be considered as the expression of a previous vulnerability.

Keywords

AdolescenceSchizophreniaChild behavior checklistPremorbid state
Type
Original article
Information
European Psychiatry , Volume 20 , Issue 4 , June 2005 , pp. 309 - 314
Copyright
Copyright © Elsevier SAS 2005

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Achenbach, TMManual for the child behavior checklist/4–18 and 1991 profile. Burlington: University of Vermont, Department of Psychiatry; 1991.Google Scholar
Amminger, GP, Rock, D, Roberts, SRelationship between childhood behavioral disturbance and later schizophrenia in the New York High Risk Project. Am J Psychiatry 1999;156(4):525–530.Google ScholarPubMed
Andreasen, NCPositive vs. negative schizophrenia: a critical evaluation. Schizophr Bull 1995;11:380–389.CrossRefGoogle Scholar
Andreasen, NCThe scale for the assessment of positive symptoms. Iowa City, IA: The University of Iowa; 1984.Google Scholar
Andreasen, NCThe scale for the assessment of negative symptoms. Iowa City, IA: The University of Iowa; 1984.Google Scholar
Baum, KM, Walker, EFChildhood behavioral precursors of adult symptom dimensions in schizophrenia. Schizophr Res 1995;16(2):111–120.CrossRefGoogle Scholar
Cannon, M, Walsh, E, Hollis, C, Kargin, M, Taylor, E, Murray, RMet al.Predictors of later schizophrenia and affective psychosis among attendees at a child psychiatry department. Br J Psychiatry 2001;178:420–426.CrossRefGoogle Scholar
Cannon, M, Jones, P, Huttunen, MO, Tanskanen, A, Huttunen, T, Rabe-Hesketh, S, Murray, RMSchool performance in Finnish children and later development of schizophrenia: a population-based longitudinal study. Arch Gen Psychiatry 1999;56(5):457–463.CrossRefGoogle ScholarPubMed
Cannon, M, Caspi, A, Moffitt, TE, Harrington, H, Taylor, A, Murray, RMet al.Evidence for early-childhood, pan-developmental impairment specific to schizophreniform disorder: results from a longitudinal birth cohort. Arch Gen Psychiatry 2002;59(5):449–456.CrossRefGoogle ScholarPubMed
Cannon, M, Jones, P, Gilvarry, CM, Rifkin, L, Mckenzie, K, Foerster, Aet al.Premorbid social functioning in schizophrenia and bipolar disorder: similarities and differences. Am J Psychiatry 1997;154:1544–1550.Google ScholarPubMed
Chambers, W, Puig Antich, J, Hirsch, M, Paez, P, Ambrosini, P, Tabrizi, Met al.The assessment of affective disorders in children and adolescent by semistructured interviews: test retest reliability of the Kiddie-Sads. Arch Gen Psychiatry 1985;42:696–702.CrossRefGoogle Scholar
Done, DJChildhood antecedents of schizophrenia and affective illness: social adjustment at ages 7 and 11. Br Med J 1994;309:699–703.CrossRefGoogle ScholarPubMed
Hans, SL, Auerbach, JG, Asarnov, JR, Styr, B, Marcus, JSocial adjustment of adolescents at risk for schizophrenia: the Jerusalem Infant Development Study. J Am Acad Child Adolesc Psychiatry 2000;39(11):1406–1414.CrossRefGoogle ScholarPubMed
Hollis, CChild and adolescent schizophrenia. A case study of premorbid developmental impairments. Br J Psychiatry 1995;166:489–495.CrossRefGoogle Scholar
Isohanni, M, Makikyro, T, Moring, J, Rasanen, P, Hakko, H, Partanen, Uet al.A comparison of clinical and research DSM-III-R diagnoses of schizophrenia in a Finnish national birth cohort. Soc Psychiatry Psychiatr Epidemiol 1997;32(5):303–308.CrossRefGoogle Scholar
Jones, P, Rodgers, B, Murray, R, Marmot, MChild developmental risk factors for adult schizophrenia in the British 1946 birth cohort. Lancet 1994;344:1398–1402.CrossRefGoogle ScholarPubMed
Karp, BI, Garvey, M, Jacobsen, LK, Frazier, JA, Hamburger, SD, Bedwell, JSet al.Abnormal neurologic maturation in adolescents with early-onset schizophrenia. Am J Psychiatry 2001;158(1):118–122.CrossRefGoogle ScholarPubMed
McClellan, J, Breiger, D, McCurry, C, Hlastala, SAPremorbid functioning in early-onset psychotic disorders. J Am Acad Child Adolesc. Psychiatry 2003;42(6):666–672.CrossRefGoogle ScholarPubMed
McGorry, PD, Jackson, HJThe recognition and management of early psychosis. Cambridge, UK: Cambridge Univerity Press; 1999.Google Scholar
Neumann, CS, Grimes, K, Walker, EF, Baum, KDevelopmental pathways to schizophrenia: behavioral subtypes. J Abnorm Psychol 1995;104(4):558–566.CrossRefGoogle ScholarPubMed
Nicolson, R, Lenane, M, Singaracharlu, S, Malaspina, D, Giedd, JN, Hamburger, SDet al.Premorbid speech and language impairments in childhood-onset schizophrenia: association with risk factors. Am J Psychiatry 2000;157(5):794–800.CrossRefGoogle ScholarPubMed
Offord, DRSchool performance of adult schizophrenics, their siblings and age mates. Br J Psychiatry 1974;125:12–19.CrossRefGoogle ScholarPubMed
Rabinowitz, J, De Smedt, G, Harvey, PD, Davidson, MRelationship between premorbid functioning and symptom severity as assessed at first-episode psychosis. Am J Psychiatry 2002;159(12):2021–2026.CrossRefGoogle Scholar
Reiter, G, Bilder, RM, Freysisen, PPremorbid achievement in first-episode schizophrenia. J Int Neuropsychol Sci 1995;1:157Google Scholar
Rossi, A, Pollice, R, Daneluzzo, E, Marinangeli, MG, Stratta, PBehavioral neurodevelopment abnormalities and schizophrenic disorder: a retrospective evaluation with the childhood behavior checklist (CBCL). Schizophr Res 2000;44(2):121–128.CrossRefGoogle Scholar
Tolbert, HAPsychoses in children and adolescents: a review. J Clin Psychiatry 1996;57:4–8.Google ScholarPubMed
Veen, ND, Selten, JP, van der Tweel, I, Feller, WG, Hoek, HW, Kahn, RSCannabis use and age at onset of schizophrenia. Am J Psychiatry 2004;161(3):501–506.CrossRefGoogle ScholarPubMed
Vourdas, A, Pipe, R, Corrigall, R, Frangou, SIncreased developmental deviance and premorbid dysfunction in early onset schizophrenia. Scizophr Res 2003;1(62):13–22.CrossRefGoogle Scholar
Warner, RThe prevention of schizophrenia: what interventions are safe and effective?. Schizophr Bull 2001;27(4):551–562.CrossRefGoogle ScholarPubMed
Wechsler, DManual for the Wechsler intellegence scale for children. 3rd ed San Antonio, TXPsychological Corporation 1991.Google Scholar
Walker, EF, Grimes, KE, Davis, DM, Smith, AJChildhood precursors of schizophrenia: facial expressions of emotion. Am J Psychiatry 1993 50(11):1654–1660.Google Scholar
Walker, E, Lewine, JRPrediction of adult-onset schizophrenia from childhood home movies of the patients. Am J Psychiatry 14781990 1052–1056.Google Scholar
Walker, EF, Diforio, D, Baum, KDevelopmental neuropathology and the precursors of schizophrenia. Acta Psychiatr Scand Suppl 1999;395:12–19.CrossRefGoogle ScholarPubMed
Werry, JS, McClellan, JM, Andrews, LKClinical features and outcome of child and adolescent schizophrenia. Schizophr Bull 1994;20:619–630.CrossRefGoogle ScholarPubMed
Weinberger, DRImplication of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 1987;44:660–669.CrossRefGoogle Scholar
Werry, JSChild and early adolescent schizophrenia: a review in the light of DSM III-R. J Autism Dev Disord 1992;22:610–614.CrossRefGoogle ScholarPubMed
Yung, AR, McGorry, PDIs pre-psychotic intervention realistic in schizophrenia and related disorders?. Aust New Zealand J Psychiatry 1997;31:799–805.CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.