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Comparative indicators of atherogenicity, body weight, gender differences in the group of depressive and non-depressive patients with cardiovascular diseases

Published online by Cambridge University Press:  13 August 2021

N. Kornetov ,
O. Molodykh  and
A. Arzhanik
N. Kornetov*
Affiliation:
Department Of Psychiatry, Addiction And Psychotherapy, Siberian States Medical Unifersity, Tomsk, Russian Federation
O. Molodykh
Affiliation:
Department Of Psychiatry, Addiction And Psychotherapy, 5th year student of the medical faculty of the Siberian State Medical Unifersity, Seversk, Russian Federation
A. Arzhanik
Affiliation:
Mathematics And Computer Science, Saint Petersburg State University, Saint Petersburg, Russian Federation
*
*Corresponding author.

Abstract

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Introduction

Many studies show that obesity, dyslipidemia, and physical inactivity are closely related to depressive spectrum of symptoms (DSS), depressive disorder (DD). DD significantly reduces the patient’s quality of life and vital activity.

Objectives

To study laboratory and physical parameters with DSS, DD in patients with cardiovascular diseases (CVD) to determine the number of patients requiring complex antidepressant therapy.

Methods

The cross-sectional study of 127 inpatients with CVD was conducted. Depression and anxiety symptoms were evaluated using HADS, anhedonia by Snaith-Hamilton Pleasure Scale (SHAPS) and pain by visual analog scale (VAS). Acquired data was statistically processed.

Results

The non-depressive patients was observed in 67 (53.0%) and 60 (47%) with DSS in CVD patients. When clinical assessing 29 (22.5%) met the criteria for major (DD), 39 (31%) for minor DD. When comparing body mass index (BMI) in patients with depression, the indicator was 31 (28.5; 33.5), in patients without depression 30 (26; 32) p <0.2828; atherogenic coefficient in patients with depression was 2.93 (2.41; 3.575), in non-depressive patients - 2.375 (2.07; 3.07) p<0.0083.

Conclusions

More than 1/5 of patients with CVD need antidepressant therapy. >90% of all patients had a high BMI regardless of gender and the presence of depression. Depressive patients in 95% of cases were obese or overweight. Severe dyslipidemia in women with depression increases the risk of CVD. Conflict of interest: No.

Disclosure

No significant relationships.

Keywords

Depressive DisorderCardiovascular diseasesobesityDyslipidemia
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S694
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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