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Delirium symptoms’ development during the intensive care unit post-surgery staying is related with reduced intraoperative cerebral oxygen saturation in the elderly subjected to cardiac surgery

Published online by Cambridge University Press:  23 March 2020

I. Bellido ,
E. Aldana ,
J.L. Valverde ,
S. Medina ,
C. Green ,
V. Campos  and
A. Gomez-Luque
I. Bellido*
Affiliation:
University of Malaga, Pharmacology and Therapeutic, Málaga, Spain
E. Aldana
Affiliation:
Xanit International Hospital, Department of Anaesthesiology, Benalmadena, Spain
J.L. Valverde
Affiliation:
Xanit International Hospital, Department of Anaesthesiology, Benalmadena, Spain
S. Medina
Affiliation:
Xanit International Hospital, Department of Anaesthesiology, Benalmadena, Spain
C. Green
Affiliation:
Xanit International Hospital, Department of Anaesthesiology, Benalmadena, Spain
V. Campos
Affiliation:
Xanit International Hospital, Department of Neurology, Benalmadena, Spain
A. Gomez-Luque
Affiliation:
Virgen de la Victoria University Hospital, Department of Anaesthesiology, Malaga, Spain
*
*Corresponding author.

Abstract

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Goal of study

Our aim was to examine whether cerebral frontal cortex O2 desaturation may be related with the development of delirium symptoms’ after cardiac surgery in the elderly during the intensive care unit (ICU) staying.

Materials and methods

A prospective, before and after, longitudinal study in II-IV ASA class patients scheduled for cardiac surgery and undergoing intravenous general anesthesia with remifentanil plus propofol was done. Clinical and surgical parameters, cardiopulmonary function, intraoperative cerebral oxygen saturation (rSO2) and bispectral index were continuously recorded and corrected throughout the surgery. Severity of delirium was represented as a score of the Intensive Care Delirium Screening Checklist (ICDSC) during the patients’ stay in the ICU under the assumption that higher ICDSC score indicated severe delirium.

Results and discussion

Patients, n = 44, 77.3% male, aged 59.9 ± 1.9 years old, scheduled to coronary (36.4%), aortic valve replacement (18.2%), mitral valve replacement (13.6%), coronary plus valve replacement (13.6%) and others (18.2%) surgery, on pump 98.4% were enrolled. A reduction of the rSO2 higher than 10% at the end of the surgery compared with basal values was detected in a 46.5% of the patients. Reduction of rSO2 higher than 10% at the end of the surgery was related with significantly higher values of delirium symptoms’ development during the intensive care unit post-surgery staying (rSO2 higher ≥ 10% 68.8 vs. rSO2 higher < 10% 31.3%, P < 0.05).

Conclusion

Delirium symptoms’ development during the intensive care unit post-surgery staying is related with reduced intraoperative cerebral oxygen saturation in the elderly subjected to cardiac surgery.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
EW231
Information
European Psychiatry , Volume 33 , Issue S1: Abstracts of the 24th European Congress of Psychiatry , March 2016 , pp. S169 - S170
Copyright
Copyright © European Psychiatric Association 2016
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