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Depression and health-related quality of life in critical COVID-19 survivors

Published online by Cambridge University Press:  01 September 2022

J. Silva ,
S. Martins ,
A.R. Ferreira ,
J. Fernandes ,
T. Vieira ,
L. Fontes ,
N. Reis ,
A. Braga ,
I. Coimbra  and
J.A. Paiva
...Show all authors
J. Silva*
Affiliation:
Faculty of Medicine University of Porto (FMUP), Fmup, Porto, Portugal
S. Martins
Affiliation:
Faculty of Medicine - University Porto, Department Of Clinical Neuroscience And Mental Health And Center for health technology and services research (cintesis), Porto, Portugal
A.R. Ferreira
Affiliation:
Faculty of Medicine - University Porto, Department Of Clinical Neuroscience And Mental Health And Center for health technology and services research (cintesis), Porto, Portugal
J. Fernandes
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
T. Vieira
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
L. Fontes
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
N. Reis
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
A. Braga
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
I. Coimbra
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal
J.A. Paiva
Affiliation:
Centro Hospitalar Universitário São João (CHUSJ), Intensive Care Medicine Department, Porto, Portugal Faculty of Medicine - University Porto, Department Of Medicine, Porto, Portugal
L. Fernandes
Affiliation:
Faculty of Medicine - University Porto, Department Of Clinical Neuroscience And Mental Health And Center for health technology and services research (cintesis), Porto, Portugal Psychiatry Service, Centro Hospitalar Universitário De São João, Porto, Portugal
*
*Corresponding author.

Abstract

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Introduction

Long-term neuropsychiatric consequences of critical illness are well known. Therefore, it is expected that critical COVID-19 patients might also present several psychiatric symptoms such as depression, with inevitable negative effect on health-related quality of life (HRQoL), commonly used as an indicator of illness and treatment impact.

Objectives

To identify depressive symptoms in critical COVID-19 survivors and to examine its association with HRQoL domains.

Methods

This preliminary study involved critical COVID-19 patients admitted into the Intensive Care Medicine Department (ICMD) of a University Hospital, between October and December of 2020. Patients with an ICMD length of stay (LoS)≤24h, terminal illness, major auditory loss, or inability to communicate at the follow-up time were excluded. From 1-2 months after discharge, all participants were evaluated by telephone at follow-up appointment, with Patient Health Questionnaire (PHQ-9) (depression) and EuroQol 5-dimension 5-level EQ-5D-5L (HRQoL). This study is part of the longitudinal MAPA project.

Results

Eighty-three patients were included with a median age of 63 years (range: 31-86) and the majority were male (63%). The most reported problems on EQ-5D-5L domains were usual activities (82%) and mobility (76%). About 27% presented depressive symptoms, and with more problems of self-care (68%vs41%; p=0.029), pain/discomfort (86%vs49%; p=0.002), and anxiety/depression (96%vs54%; p<0.001).

Conclusions

These preliminary results are in line in previous studies in critical COVID-19 survivors, with depression being associated with worse HRQoL. Bearing this in mind, follow-up approaches with an early screening and treatment of these psychiatric symptoms will be fundamental to optimize the recovery of these patients.

Disclosure

No significant relationships.

Keywords

Covid-19Quality-of-lifeDepressionCritical illness
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S377
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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