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Duration of untreated psychosis and the long-term course of schizophrenia

Published online by Cambridge University Press:  16 April 2020

L. de Haan ,
M. van der Gaag  and
J. Wolthaus
L. de Haan
Affiliation:
Adolescent Clinic, Academic Medical Center, University of Amsterdam,Amsterdam, The Netherlands
M. van der Gaag
Affiliation:
University of Leiden, Department of Psychiatry and Parnassia Research Center,The Hague, The Netherlands
J. Wolthaus*
Affiliation:
Adolescent Clinic, Academic Medical Center, University of Amsterdam,Amsterdam, The Netherlands
*
*Correspondence and reprints: L. de Haan, Academic Medical Center, University of Amsterdam, Department of Psychiatry, Postbox 22700, 1100 DE Amsterdam, The Netherlands
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Summary

This study examines the relationship between duration of untreated psychosis (DUP) and long-term symptomatic and social outcome in 205 patients with schizophrenia, whose parents are member of a consumer organisation. We found only a tendency that longer DUP was related to negative symptoms, but no relation to other outcome domains. The results of this study do not support antipsychotic intervention at the earliest sign of psychosis in order to ‘protect the brain’.

Keywords

duration of untreated psychosislong-term courseschizophrenia
Type
Original article
Information
European Psychiatry , Volume 15 , Issue 4 , June 2000 , pp. 264 - 267
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2000

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