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Efficacy of acetylsalicylic acid in schizophrenia: a literature review

Published online by Cambridge University Press:  27 August 2024

A. Aissa ,
S. Jedda ,
F. Askri ,
O. Maatouk ,
U. Ouali ,
Y. Zgueb  and
R. Jomli
A. Aissa*
Affiliation:
1Psychiatry A, Razi Hospital, Manouba 2Psychiatry, Faculty of Medicine of Tunis, Tunis, Tunisia
S. Jedda
Affiliation:
1Psychiatry A, Razi Hospital, Manouba
F. Askri
Affiliation:
1Psychiatry A, Razi Hospital, Manouba
O. Maatouk
Affiliation:
1Psychiatry A, Razi Hospital, Manouba
U. Ouali
Affiliation:
1Psychiatry A, Razi Hospital, Manouba
Y. Zgueb
Affiliation:
1Psychiatry A, Razi Hospital, Manouba
R. Jomli
Affiliation:
1Psychiatry A, Razi Hospital, Manouba
*
*Corresponding author.

Abstract

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Introduction

There has been growing evidence to support the hypothesis that inflammation is involved in the pathogenesis of schizophrenia.

Objectives

The aim of the present literature review was to assess the efficacy of acetylsalicylic acid (ASA) as an adjuvant agent in the treatment of an acute exacerbation of schizophrenia.

Methods

We searched randomized clinical trials based on regular searches of MEDLINE, Embase, PubMed.

Results

We included four studies. The results were in favor of the efficacy of ASA in the study where authors targeted early psychosis. Illness duration seems to predict response to anti-inflammatory agents.

Conclusions

Further studies of early stages of schizophrenia are helpful.

Disclosure of Interest

None Declared

Type
Abstract
Information
European Psychiatry , Volume 67 , Special Issue S1: Abstracts of the 32nd European Congress of Psychiatry , April 2024 , pp. S725
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of European Psychiatric Association
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