Hostname: page-component-78c5997874-g7gxr Total loading time: 0 Render date: 2024-11-10T06:54:26.616Z Has data issue: false hasContentIssue false

Failure to find association between childhood abuse and cognition in first-episode psychosis patients

Published online by Cambridge University Press:  15 April 2020

L. Sideli*
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK Department of Experimental Biomedicine and Clinical Neuroscience, University of Palermo, Palermo, Italy
H.L. Fisher
Affiliation:
MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK
M. Russo
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
R.M. Murray
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK
S.A. Stilo
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK
B.D.R. Wiffen
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK
J.A. O’Connor
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK
M. Aurora Falcone
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK Department of Psychology, Institute of Psychiatry, King's College London, London, UK
S.M. Pintore
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK
L. Ferraro
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK Department of Experimental Biomedicine and Clinical Neuroscience, University of Palermo, Palermo, Italy
A. Mule’
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK Department of Experimental Biomedicine and Clinical Neuroscience, University of Palermo, Palermo, Italy
D. La Barbera
Affiliation:
Department of Experimental Biomedicine and Clinical Neuroscience, University of Palermo, Palermo, Italy
C. Morgan
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK
M. Di Forti
Affiliation:
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK
*
*Corresponding author. Department of Experimental Biomedicine and Clinical Neuroscience, Section of Psychiatry, via G. La Loggia 1, 90129 Palermo, Italy. Tel.: +39 916555170; fax: +39 916555165. E-mail address: lucia.sideli@gmail.com (L. Sideli).
Get access

Abstract

This study investigated the relationship between severe childhood abuse and cognitive functions in first-episode psychosis patients and geographically-matched controls. Reports of any abuse were associated with lower scores in the executive function domain in the control group. However, in contrast with our hypothesis, no relationships were found amongst cases.

Type
Short communication
Copyright
Copyright © 2013 Elsevier Masson SAS

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Aas, M.Dazzan, P.Fisher, H.L.Morgan, C.Morgan, K.Reichenberg, A.et al.Childhood trauma and cognitive function in first-episode affective and non-affective psychosis. Schizophr Res 2011;129(1):1219.CrossRefGoogle ScholarPubMed
Aas, M.Dazzan, P.Mondelli, V.Toulopoulou, T.Reichenberg, A.Di Forti, M.et al.Abnormal cortisol awakening response predicts worse cognitive function in patients with first-episode psychosis. Psychol Med 2011;41(3):463476.CrossRefGoogle ScholarPubMed
American Psychiatric, Association, Diagnostic and statistical manual of mental disorders. 4th edn.Washington, DC: American Psychiatric Association; 2000.[text revision (DSM-IV-TR)].Google Scholar
Bebbington, P.Nayani, T.The Psychosis Screening Questionnaire. Int J Methods Psychiatr Res 1995;5:1119.Google Scholar
Bifulco, A.Bernazzani, O.Moran, P.M.Jacobs, C.The childhood experience of care and abuse questionnaire (CECAQ): validation in a community series. Br J Clin Psychol 2005;44(4):563581.CrossRefGoogle Scholar
Carpenter, L.L.Shattuck, T.T.Tyrka, A.R.Geracioti, T.D.Price, L.H.Effect of childhood physical abuse on cortisol stress response. Psychopharmacology (Berl) 2011;214(1):367375.CrossRefGoogle ScholarPubMed
Cohen, R.A.Grieve, S.Hoth, K.F.Paul, R.H.Sweet, L.Tate, D.et al.Early life stress and morphometry of the adult anterior cingulate cortex and caudate nuclei. Biol Psychiatry 2006;59(10):975982.CrossRefGoogle ScholarPubMed
Di Forti, M.Morgan, C.Dazzan, P.Pariante, C.Mondelli, V.Marques, T.R.et al.High-potency cannabis and the risk of psychosis. Br J Psychiatry 2009;195(6):488491.CrossRefGoogle ScholarPubMed
Elzinga, B.M.Roelofs, K.Tollenaar, M.S.Bakvis, P.van Pelt, J.Spinhoven, P.Diminished cortisol responses to psychosocial stress associated with lifetime adverse events: a study among healthy young subjects. Psychoneuroendocrinology 2008;33(2):227237.CrossRefGoogle ScholarPubMed
Fisher, H.L.Jones, P.B.Fearon, P.Craig, T.K.Dazzan, P.Morgan, K.et al.The varying impact of type, timing and frequency of exposure to childhood adversity on its association with adult psychotic disorder. Psychol Med 2010;40(12):19671978.CrossRefGoogle ScholarPubMed
Fisher, H.L.Craig, T.K.Fearon, P.Morgan, K.Dazzan, P.Lappin, J.et al.Reliability and comparability of psychosis patients’ retrospective reports of childhood abuse. Schizophr Bull 2011;37(3):546553.CrossRefGoogle ScholarPubMed
Hart, H.Rubia, K.Neuroimaging of child abuse: a critical review. Front Hum Neurosci 2012;6:52.CrossRefGoogle ScholarPubMed
Klaassens, E.R.van Noorden, M.S.Giltay, E.J.van Pelt, J.van Veen, T.Zitman, F.G.Effects of childhood trauma on HPA-axis reactivity in women free of lifetime psychopathology. Prog Neuropsychopharmacol Biol Psychiatry 2009;33(5):889894.CrossRefGoogle ScholarPubMed
Lysaker, P.H.Meyer, P.Evans, J.D.Marks, K.A.Neurocognitive and symptom correlates of self-reported childhood sexual abuse in schizophrenia spectrum disorders. Ann Clin Psychiatry 2001;13(2):8992.CrossRefGoogle ScholarPubMed
McCrory, E.De Brito, S.A.Viding, E.Research Review:, The neurobiology and genetics of maltreatment and adversity. J Child Psychol Psychiatry 2011;51(10):10791095.CrossRefGoogle Scholar
McGuffin, P.Farmer, A.Harvey, I.A polydiagnostic application of operational criteria in studies of psychotic illness: development and reliability of the OPCRIT system. Arch Gen Psychiatry 1991;48(8):764770.CrossRefGoogle ScholarPubMed
Mills, R.Alati, R.O’Callaghan, M.Najman, J.M.Williams, G.M.Bor, W.et al.Child abuse and neglect and cognitive function at 14 years of age: findings from a birth cohort. Pediatrics 2011;127(1):410.CrossRefGoogle ScholarPubMed
Nelson, H.E.Willison, J.National Adult Reading Test manual. 2nd edn. Windsor: NFER-Nelson; 1991.Google Scholar
Perez, C.M.Widom, C.S.Childhood victimization and long-term intellectual and academic outcomes. Child Abuse Negl 1994;18(8):617633.CrossRefGoogle ScholarPubMed
Reitan, R.M.Validity of the Trail Making Test as an indicator of organic brain damage. Percept Mot Skills 1958;8:271276.CrossRefGoogle Scholar
Savitz, J.B.Van Der Merwe, L.Stein, D.J.Solms, M.Ramesar, R.S.Neuropsychological task performance in bipolar spectrum illness: genetics, alcohol abuse, medication and childhood trauma. Bipolar disorders 2008;10(4):479494.CrossRefGoogle ScholarPubMed
Schenkel, L.S.Spaulding, W.D.DiLillo, D.Silverstein, S.M.Histories of childhood maltreatment in schizophrenia: relationships with premorbid functioning, symptomatology, and cognitive deficits. Schizophr Res 2005;76(2–3):273286.CrossRefGoogle ScholarPubMed
Shannon, C.Douse, K.McCusker, C.Feeney, L.Barrett, S.Mulholland, C.The association between childhood trauma and memory functioning in schizophrenia. Schizophr Bull 2011;37(3):531537.CrossRefGoogle Scholar
Tomoda, A.Navalta, C.P.Polcari, A.Sadato, N.Teicher, M.H.Childhood sexual abuse is associated with reduced gray matter volume in visual cortex of young women. Biol Psychiatry 2009;66(7):642648. [Epub 2009/06/30].CrossRefGoogle ScholarPubMed
Wechsler, D.Wechsler Adult Intelligence Scale – Third edition: administration and scoring manual. San Antonio: TX: The Psychological Corporation; 1997.Google Scholar
Wechsler, D.Wechsler Memory Scale – Third edition: administration and scoring manual. San Antonio: TX: The Psychological Corporation; 1997.Google Scholar
Yeudall, L.T.Fromm, D.Reddon, J.R.Stefanyk, W.O.Normative data stratified by age and sex for 12 neuropsychological tests. J Clin Psychol 1986;42:918946.3.0.CO;2-Y>CrossRefGoogle Scholar
Zanelli, J.Reichenberg, A.Morgan, K.Fearon, P.Kravariti, E.Dazzan, P.et al.Specific and generalized neuropsychological deficits: a comparison of patients with various first-episode psychosis presentations. Am J Psychiatry 2010;167(1):7885.CrossRefGoogle ScholarPubMed
Submit a response

Comments

No Comments have been published for this article.