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Frailty index as a clinical measure of biological age in psychiatry

Published online by Cambridge University Press:  13 August 2021

F.S. Bersani
F.S. Bersani*
Affiliation:
Department Of Human Neurosciences, Sapienza University of Rome, Rome, Italy

Abstract

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The concepts of “accelerated biological ageing” and “premature biological senescence” have been receiving increasing attention in relation to psychiatric diseases, with clinical, epidemiological and molecular observations suggesting that psychopathological processes can have significant relationships with aging-related phenomena. The deficit accumulation model postulates that the individual’s biological age and functional status is related to the amount of health deficits accumulated over time and that one’s biological age can be estimated by summarizing health deficits in a single continuous variable, the so-called “frailty index” (FI). In this presentation it will be discussed the possibility that the FI, which condenses information arising from multidimensional evaluations, represents a potential clinically-useful macroscopic indicator of biological age which can add relevant information to the measurements currently implemented in the study of accelerated biological age in psychiatric diseases.

Disclosure

No significant relationships.

Keywords

comorbidityaccelerated biological agingfrailty indexdeficit accumulation model
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S63
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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