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Interrelation of visual and olfactory impairments in schizophrenia

Published online by Cambridge University Press:  13 August 2021

M. Tumova ,
V. Karpinskaya ,
E. Bezgacheva ,
L. Muslimova ,
E. Bigday  and
M. Ivanov
M. Tumova*
Affiliation:
Psychiatry, V.M. Bekhterev National Medical Research Center Psychiatry and Neurology, St. Petersburg, Russian Federation
V. Karpinskaya
Affiliation:
Neurovisualization, N.P. Bekhtereva Institute of Head RAS, St-Petersburg, Russian Federation
E. Bezgacheva
Affiliation:
Laboratory Of Olfactory, I.P. Pavlov Institute of Physiology RAS, Saint-Petersburg, Russian Federation
L. Muslimova
Affiliation:
Psychiatry, V.M. Bekhterev National Medical Research Center Psychiatry and Neurology, St. Petersburg, Russian Federation
E. Bigday
Affiliation:
Laboratory Of Olfactory, I.P. Pavlov Institute of Physiology RAS, Saint-Petersburg, Russian Federation
M. Ivanov
Affiliation:
Psychiatry, V.M. Bekhterev National Medical Research Center Psychiatry and Neurology, St. Petersburg, Russian Federation
*
*Corresponding author.

Abstract

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Introduction

In schizophrenia, there are disorders in all sensory modalities, but the regularities of their occurrence, their pathogenesis and attitude towards cognitive functions are not sufficiently studied.

Objectives

Examine the interrelation between the dysfunctions in different analysers (olfactory and visual) and their dependence on the duration of the disease and the severity of psychotic symptoms and cognitive deficit in schizophrenic patients (F20 according to ICD 10 criteria).

Methods

All subjects were determined the threshold of olfactory sensitivity to n-butanol, the ability to discriminate against odors and the amount of error in comparing the same sections. Cognitive functions were evaluated using the BACS scale.

Results

The inverse correlation between the value of the visual assessment error and the reduction of the threshold of olfactory sensitivity (r=- 0.56; p < 0.05) and the inverse correlation between the value of the visual assessment error and the ability to discriminate smells (0.64; p < 0.05) were revealed. There are no significant correlations between the duration of the disease and sensory disturbances. Olfactory and visual disturbances in schizophrenic patients were connected with cognitive functions ((r=-0,62; p< 0,05 and r=-0,84, p< 0,001 accordingly).

Conclusions

The data confirm that sensory impairments have a common pathogenesis and are closely related to cognitive deficits. Sensory and cognitive deficits in schizophrenia may be the result of top-down regulation failure.

Disclosure

No significant relationships.

Keywords

schizophréniavisual and olfactory impairmentscognition functions
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S162 - S163
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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