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Management of treatment resistant depression: A comparison between French expert consensus guidelines and international evidence based guidelines

Published online by Cambridge University Press:  23 March 2020

T. Charpeaud ,
A. Yrondi ,
W. El-Hage ,
M. Leboyer ,
E. Haffen ,
P.M. Llorca ,
P. Courtet  and
B. Aouizerate
T. Charpeaud
Affiliation:
CHU de Clermont-Ferrand, service de psychiatrie de l’adulte B, Clermont-Ferrand, France
A. Yrondi
Affiliation:
CHU de Toulouse, service de psychiatrie de l’adulte, Toulouse, France
W. El-Hage
Affiliation:
CHU de Tours, service de psychiatrie de l’adulte, Tours, France
M. Leboyer
Affiliation:
Centre hospitalier Albert-Chenevier, service de psychiatrie de l’adulte, Créteil, France
E. Haffen
Affiliation:
CHU de Besançon, service de psychiatrie de l’adulte, Besançon, France
P.M. Llorca
Affiliation:
CHU de Clermont-Ferrand, service de psychiatrie de l’adulte B, Clermont-Ferrand, France
P. Courtet
Affiliation:
CHU de Montpellier, urgences et post-urgences, Montpellier, France
B. Aouizerate
Affiliation:
Centre hospitalier Charles-Perrens, pôle de psychiatrie, Bordeaux, France

Abstract

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Expert consensus guidelines rely on a relevant methodological procedure complementary to based-evidence recommendations. They aim at offering support strategies derived from expert consensus for clinical situations where the levels of evidence are either absent or insufficient. Recommendations for resistant depressive disorders proposed by french association for biological psychiatry and fondamental foundation, were based on responses from 36 highly specialized experts in this field. They were invited to complete a comprehensive questionnaire with 118 issues. The questions raised covered a wide range of aspects from the evaluation of therapeutic resistance and clinical conditions increasing the risk for treatment failure to the adopted therapeutic strategies organized according the effects of previous treatment lines. Specific populations/situations especially including elderly, comorbidities (anxiety disorders, personality disorders and addictions) were also been studied through specific questions. Such recommendations are intended to substantially help the decision and therapeutic choice of clinician implied in the management of resistant depressive disorders in everyday clinical practice. We propose in this communication to compare the results of these recommendations with the various data from the evidence-based guidelines in order to demonstrate their complementarity for the management of resistant depressive disorders.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
e-Poster viewing: Cultural psychiatry
Information
European Psychiatry , Volume 41 , Issue S1: Abstract of the 25th European Congress of Psychiatry , April 2017 , pp. S525
Copyright
Copyright © European Psychiatric Association 2017
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