Hostname: page-component-78c5997874-v9fdk Total loading time: 0 Render date: 2024-11-10T07:12:07.563Z Has data issue: false hasContentIssue false
  • English
  • Français

Nefazodone may inhibit the metabolism of carbamazepine: three case reports

Published online by Cambridge University Press:  16 April 2020

L. Roth  and
G. Bertschy
L. Roth
Affiliation:
Clinique de Psychiatrie Adulte, Belle-Idée, 2 ch. du Petit Bel-Air, 1225, Chêne-Bourg, Switzerland
G. Bertschy*
Affiliation:
Clinique de Psychiatrie Adulte, Belle-Idée, 2 ch. du Petit Bel-Air, 1225, Chêne-Bourg, Switzerland
*
*Correspondence and reprints. E-mail address:gilles.bertschy@hcuge.ch (G. Bertschy).
Get access

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Short communication
Information
European Psychiatry , Volume 16 , Issue 5 , August 2001 , pp. 320 - 321
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2001

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Ashton, AKWolin, RE.Nefazodone-induced carbamazepine toxicity 〚letter〛. Am J Psychiatry 1996; 15: 733.Google Scholar
Greene, DSBarbhaiya, RH.Clinical pharmacokinetics of nefazodone. Clin Pharmacokinet 1997; 3: 260–75.CrossRefGoogle Scholar
Greene, DSSalazar, DEDockens, RCKroboth, PBarbhaiya, RH.Coadministration of nefazodone and benzodiazepines: III. A pharmacokinetic interaction study with alprazolam. J Clin Psychopharmacol 1995; 1: 399–408.CrossRefGoogle Scholar
Kharasch, EDHankins, DCJubert, CThummel, KETaraday, JK.Lack of single-dose disulfiram effects on cytochrome P-450 2C9, 2C19, 2D6, and 3A4 activities: evidence for specificity toward P-450 2E1. Drug Metab Dispos 1999; 2: 717–23.Google Scholar
Kroboth, PDFolan, MMLush, RMChaikin, PCShukla, UABarbhaiya, R., et al. Coadministration of nefazodone and benzodiazepines: I. Pharmacodynamic assessment. J Clin Psychopharmacol 1995; 1: 306–19.CrossRefGoogle Scholar
Laroudie, CSalazar, DECosson, JPCheuvart, BIstin, BGirault, J., et al. Carbamazepine-nefazodone interaction in healthy subjects. J Clin Psychopharmacol 2000; 2: 46–53.CrossRefGoogle Scholar
Madan, AParkinson, AFaiman, MD.Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N, N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram. Drug Metab Dispos 1995; 2: 1153–62.Google Scholar
Robinson, DSRoberts, DLSmith, JMStringfellow, JCKaplita, SBSeminara, JA., et al. The safety profile of nefazodone. J Clin Psychiatry 5Suppl21996 31–38.Google Scholar
Spina, EPisani, FPerucca, E.Clinically significant pharmacokinetic drug interactions with carbamazepine. An update. Clin Pharmacokinet 1996; 3: 198–214.CrossRefGoogle Scholar
Submit a response

Comments

No Comments have been published for this article.