Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-13T05:48:12.606Z Has data issue: false hasContentIssue false

Objective QbTest and subjective evaluation of stimulant treatment in adult attention deficit-hyperactivity disorder

Published online by Cambridge University Press:  15 April 2020

Get access

Abstract

Purpose:

To evaluate the QbTest as an objective measure versus self-reported ADHD Rating Scale (ADHD-RS) before and during stimulant treatment in adults with ADHD.

Patients and methods:

We used the subjective ADHD Rating Scale (ADHD-RS), and the objective computerized QbTest, which is a 20-minute unconditional identical pairs test that measures attention, impulsivity, and also hyperactivity using a motion-tracking system. Patients were assessed before (baseline) and during medical treatment with stimulants (follow-up) in an observational study design.

Results:

Data of n = 145 patients at baseline and n = 82 patients at follow-up were analyzed. There were significant symptom reductions on all symptom domains, but correlations between the tests were weak. Improvement on the QbTest was independent of the patient's age, gender, educational level, ADHD subtype, co-morbid disorders, and use of other medications. Patients with worst QbTest results at baseline showed most improvement at follow-up. The QbTest was more sensitive to medication effects than the ADHD-RS. QbTest objectified clinical significant medication effect in 54% of patients who subjectively did not report any clinical effects.

Discussion:

Symptoms dimensions of objective and subjective tests refer to different psychological constructs.

Conclusion:

The QbTest is a valuable addition to existing subjective measures to assess medication effects in ADHD patients who have difficulties reporting treatment effects.

Type
Original article
Copyright
Copyright © European Psychiatric Association 2020

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

APA Diagnostic and statistical manual of mental disorders (DSM-IV), 4th ed., Washington DC: American Psychiatric Association; 1994.Google Scholar
Dopfner, M., Steinhausen, H.C., Coghill, D., Dalsgaard, S., Poole, L., Ralston, S.J., et al.Cross-cultural reliability and validity of ADHD assessed by the ADHD rating scale in a pan-European study. Eur Child Adolesc Psychiatry 2006;15.Google Scholar
Edebol, H., Helldin, L., Norlander, T.. Measuring adult attention deficit hyperactivity disorder using the quantified behavior test plus. PsyCh J 2013;2:4862.CrossRefGoogle ScholarPubMed
Faraone, S.V.. Understanding the effect size of lisdexamfetamine dimesylate for treating ADHD in children and adults. J Atten Disord 2012;16:128137.CrossRefGoogle ScholarPubMed
Faraone, S.V., Spencer, T., Aleardi, M., Pagano, C., Biederman, J.. Meta-analysis of the efficacy of methylphenidate for treating adult attention-deficit/hyperactivity disorder. J Clin Psychopharmacol 2004;24:2429.CrossRefGoogle ScholarPubMed
Faraone, S.V., Biederman, J., Mick, E.. The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies. Psychol Med 2006;36:159165.CrossRefGoogle ScholarPubMed
Fayyad, J., De Graaf, R., Kessler, R., Alonso, J., Angermeyer, M., Demyttenaere, K., et al.Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder. Br J Psychiatry 2007;190:402429.CrossRefGoogle ScholarPubMed
Koesters, M., Becker, T., Kilian, R., Fegert, J.M., Weinmann, S.. Limits of meta-analysis: methylphenidate in the treatment of adult attention-deficit hyperactivity disorder. J Psychopharmacol 2009;23:733744.CrossRefGoogle ScholarPubMed
Kooij, J.J.Adult ADHD: diagnostic assessment and treatment, 3rd ed. London: Springer; 2013.CrossRefGoogle Scholar
Kooij, J.J., Bijlenga, D.. The circadian rhythm in adult attention-deficit/hyperactivity disorder: current state of affairs. Expert Rev Neurother 2013;13:11071116.CrossRefGoogle ScholarPubMed
Kooij, J.J., Francken, M.H.Diagnostic interview for ADHD in adults version 2.0 (DIVA 2.0) [Dutch: Diagnostisch Interview voor ADHD bij volwassenen]. 2010. The Hague, The Netherlands: DIVA Foundation; Available online at: www.divacenter.eu.Google Scholar
Kooij, J.J., Buitelaar, J.K., van den Oord, E.J., Furer, J.W., Rijnders, C.A., Hodiamont, P.P.. Internal and external validity of attention-deficit hyperactivity disorder in a population-based sample of adults. Psychol Med 2005;35:817827.CrossRefGoogle Scholar
Lis, S., Baer, N., Stein-En-Nosse, C., Gallhofer, B., Sammer, G., Kirsch, P.. Objective measurement of motor activity during cognitive performance in adults with attention-deficit/hyperactivity disorder. Acta Psychiatrica Scandinavica 2010;122:285294.CrossRefGoogle ScholarPubMed
Mattingly, G.W., Weisler, R.H., Young, J., Adeyi, B., Dirks, B., Babcock, T., et al.Clinical response and symptomatic remission in short- and long-term trials of lisdexamfetamine dimesylate in adults with attention-deficit/hyperactivity disorder. BMC Psychiatry 2013 13.Google Scholar
McGoey, K.E., DuPaul, G.J., Haley, E., Shelton, T.L.. Parent and teacher ratings of attention-deficit/hyperactivity disorder in preschool: the ADHD rating scale-IV preschool version. J Psychopathol Behav Assess 2007;29:269276.CrossRefGoogle Scholar
Reh, V., Schmidt, M., Lam, L., Schimmelmann, B.G., Hebebrand, J., Rief, W., et al.Behavioral Assessment of Core ADHD Symptoms Using the QbTest. J Atten Disord 2013.Google ScholarPubMed
Riccio, C.A., Reynolds, C.R.. Continuous performance tests are sensitive to ADHD in adults but lack specificity. A review and critique for differential diagnosis. Ann N Y Acad Sci 2001;931:113139.CrossRefGoogle ScholarPubMed
Söderström, S., Pettersson, R., Nilsson, K.W.. Quantitative and subjective behavioural aspects in the assessment of attention-deficit hyperactivity disorder (ADHD) in adults. Nord J Psychiatry 2013;68(1):3037.CrossRefGoogle ScholarPubMed
Spencer, T.J., Biederman, J., Mick, E.. Attention-deficit/hyperactivity disorder: diagnosis, lifespan, comorbidities, and neurobiology. Ambul Pediatr 71S2007 7381.CrossRefGoogle ScholarPubMed
Szomlaiski, N., Dyrborg, J., Rasmussen, H., Schumann, T., Koch, S.V., Bilenberg, N.. Validity and clinical feasibility of the ADHD rating scale (ADHD-RS). A Danish Nationwide Multicenter Study. Acta Paediatr 2009;98:397402.CrossRefGoogle ScholarPubMed
Toplak, M.E., West, R.F., Stanovich, K.E.Do performance-based measures and ratings of executive function assess the same construct?. J Child Psychol Psychiatry 2012.Google ScholarPubMed
lberstadt, F.QbTest technical manual. Stockholm, Sweden: Qbtech AB; 2012.Google Scholar
Wehmeier, P.M., Schacht, A., Wolff, C., Otto, W.R., Dittmann, R.W., Banaschewski, T.Neuropsychological outcomes across the day in children with attention-deficit/hyperactivity disorder treated with atomoxetine: results from a placebo-controlled study using a computer-based continuous performance test combined with an infra-red motion-tracking device. J Child Adolesc Psychopharmacol 2011;21:433444.CrossRefGoogle Scholar
Submit a response

Comments

No Comments have been published for this article.