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A one year prevalence study of schizophrenia on Reunion Island

Published online by Cambridge University Press:  16 April 2020

M Jay ,
P Gorwood ,
J Feingold  and
M Leboyer
M Jay
Affiliation:
Saint Paul Psychiatric Hospital, Reunion Island, France
P Gorwood*
Affiliation:
Genetic Epidemiology, INSERM Unit 155, Université Paris VII, Paris, France Psychiatric Department, Louis Mourier Hospital, 178, rue des Renouillers, 92701Colombes, France
J Feingold
Affiliation:
Psychiatric Department, Louis Mourier Hospital, 178, rue des Renouillers, 92701Colombes, France
M Leboyer
Affiliation:
Psychiatric Department, Louis Mourier Hospital, 178, rue des Renouillers, 92701Colombes, France Psychiatric Department, Pitié-Salpêtrière Hospital, Paris, France
*
*Correspondence and reprints to the Colombes address.
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Summary

Review of geographical comparisons of the prevalence of schizophrenic disorders found a ten-fold range difference between geographical contiguous groups, with high and low prevalence pockets. We performed a 1-year prevalence study of schizophrenia in a limited area of Reunion Island in the Indian Ocean, and analysed the prevalence variability in contiguous regions of this area. We found one of the highest reported age-corrected (above 15 years) 1-year prevalence of schizophrenia (14.9 per thousand). Large discrepancies in the distribution of prevalence rates of schizophrenia were observed between the five towns analysed. Interestingly, when a higher prevalence was observed, it was highly correlated with an increase of the percentage of familial cases (r = 0.989, df = 3, P = 0.0014). Presence of founder effect often described in geographical isolates could explain the high prevalence rate and the heterogeneity between towns observed in our sample.

Keywords

schizophreniafamilial case prevalencefounder effect
Type
Original article
Information
European Psychiatry , Volume 12 , Issue 6 , 1997 , pp. 284 - 288
Copyright
Copyright © European Psychiatric Association 1997

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