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Parkinson’s disease and depression

Published online by Cambridge University Press:  13 August 2021

A. Maamri ,
H. Ghabi  and
H. Zalila
A. Maamri
Affiliation:
Faculty Of Medincine Of Tunis, RAZI HOSPITAL, TUNIS, Tunisia Psychiatry, Outpatient Service, Razi Hospital, Manouba, Tunisia
H. Ghabi*
Affiliation:
Outpatients Ward Of Psychiatry, Razi hospital, Manouba, Tunisia
H. Zalila
Affiliation:
Faculty Of Medincine Of Tunis, RAZI HOSPITAL, TUNIS, Tunisia Psychiatry, Outpatient Service, Razi Hospital, Manouba, Tunisia Outpatients Ward Of Psychiatry, Razi hospital, Manouba, Tunisia
*
*Corresponding author.

Abstract

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Introduction

Parkinson’s disease has long been considered as a neurodegenerative disorder of pure motor expression. Motor dysfunction in Parkinson’s disease and other parkinsonian disorders is frequently accompanied by nonmotor signs and symptoms, including cognitive impairment, apathy, anxiety, and depression. Among psychiatric disorders comorbid with Parkinson’s disease, depression is probably the most important in terms of frequency and impact.

Objectives

The aim of this presentation was to illustrate the importance of considering depressive symptoms in patients with Parkinson’s disease.

Methods

A case report describing a patient with depressive symptoms in a patient with Parkinson’s disease and literature review.

Results

We report a case of a 57-year-old woman who presented symptoms of Parkinson’s disease for two years. She was treated with Benserazide (Madopar). She was referred to our department for depressive symptomatology. The patient suffered from fatigue, insomnia, loss of sexual desire, sadness, anhedonia, and social withdrawal during the last three months. The diagnosis of depression was not immediately retained. Finally, a major depressive episode was diagnosed. Fluoxetine (20mg per day) was prescribed with clinical improvement.

Conclusions

The diagnosis of a depressive episode is most often complex, due to an overlap symptomatic of both disorders. The depression comorbid to Parkinson’s disease because of its frequency and impact, requires specific identification and management early.

Keywords

parkinson’s diseaseDepression
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S240
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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