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Predictors of compliance with neuroleptic medication among inpatients with schizophrenia: a discriminant function analysis

Published online by Cambridge University Press:  16 April 2020

G. Donohoe ,
N. Owens ,
C. O’Donnell ,
T. Burke ,
L. Moore ,
A. Tobin  and
E. O’Callaghan
G. Donohoe
Affiliation:
Department of Adult Psychiatry, Cluain Mhuire Service, Hospitaller Order John of God, Dublin, Ireland Department of Psychology, University College Dublin, Dublin, Ireland
N. Owens
Affiliation:
Department of Adult Psychiatry, Cluain Mhuire Service, Hospitaller Order John of God, Dublin, Ireland
C. O’Donnell
Affiliation:
Department of Adult Psychiatry, Cluain Mhuire Service, Hospitaller Order John of God, Dublin, Ireland
T. Burke
Affiliation:
Department of Psychology, University College Dublin, Dublin, Ireland
L. Moore
Affiliation:
Department of Adult Psychiatry, Cluain Mhuire Service, Hospitaller Order John of God, Dublin, Ireland
A. Tobin
Affiliation:
Eli Lilly Pharmaceuticals, (Ireland)
E. O’Callaghan*
Affiliation:
Department of Adult Psychiatry, Cluain Mhuire Service, Hospitaller Order John of God, Dublin, Ireland
*
*Correspondence and reprints: Cluain Mhuire Service, Newtownpark Avenue, Blackrock, Co. Dublin, Ireland. E-mail address: eadbhard@indigo (E. O'Callaghan).
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Summary

Objective. To identify clinically useful predictors of adherence to medication among persons with schizophrenia. Method. We evaluated levels of compliance with neuroleptic medication among 32 consecutive admissions with DSM-III-R schizophrenia from a geographically defined catchment area using a compliance interview. We also assessed symptomatology, insight, neurological status and memory. Results. Less than 25% of consecutive admissions reported being fully compliant. Drug attitudes were the best predictor of regular compliance, symptomatology the best predictor of noncompliance, and memory the best predictor of partial compliance with neuroleptic medication. Conclusions. These data emphasise the complexity of factors that influence whether a person adheres to his medication regimen. Furthermore, they suggest that these factors may vary within the same person over time.

Keywords

adherencecompliancedrug attitudesinsightneurolepticsschizophrenia
Type
Original article
Information
European Psychiatry , Volume 16 , Issue 5 , August 2001 , pp. 293 - 298
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2001

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