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A prospective study of bipolar disorder vulnerability in relation to behavioural activation, behavioural inhibition and dysregulation of the Behavioural Activation System

Published online by Cambridge University Press:  23 March 2020

R.C. Dempsey ,
P.A. Gooding  and
S.H. Jones
R.C. Dempsey*
Affiliation:
Division of Psychology and Mental Health, School of Health Sciences, The University of Manchester, ManchesterM13 9PL, UK Staffordshire Centre for Psychological Research, School of Life Sciences and Education, Staffordshire University, Science Centre, Leek Road , Stoke-on-TrentST4 2DF, UK
P.A. Gooding
Affiliation:
Division of Psychology and Mental Health, School of Health Sciences, The University of Manchester, ManchesterM13 9PL, UK
S.H. Jones
Affiliation:
Spectrum Centre for Mental Health Research, Lancaster University, LancasterLA1 4YT, UK
*
*Corresponding author. Staffordshire Centre for Psychological Research, School of Life Sciences & Education, Staffordshire University, Science Centre, Leek Road, Stoke-on-Trent ST4 2DF, United Kingdom. Tel.: +44 0 1782 294886; fax: +44 0 1782 294986. E-mail address:robert.dempsey@staffs.ac.uk (R.C. Dempsey)
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Abstract

Background:

The weak regulation, or “dysregulation”, of the Behavioural Activation System (BAS) is implicated in the development and recurrence of bipolar disorder. However, there has been a lack of prospective studies investigating the predictive role of BAS dysregulation in relation to bipolar-vulnerability. Furthermore, no studies have tested the prospective predictive utility of the DYS self-report measure of BAS dysregulation in an analogue sample. The goal of the current study was to redress this gap.

Methods:

Participants (n = 127) completed baseline self-report measures of mood symptoms (Internal States Scale [ISS]), the Hypomanic Personality Scale (HPS), behavioural activation, inhibition and dysregulation of BAS (BIS/BAS and DYS), and at six months, the Mood Disorders Questionnaire (MDQ).

Results:

Linear regression analysis indicated a significant main effect of BAS Dysregulation, and a significant interaction between BIS and BAS Fun Seeking, on prospective MDQ scores whilst controlling for baseline mood symptoms and HPS scores. The interaction effect indicated that the relationship between high BAS Fun Seeking and follow-up MDQ scores was strongest when BIS scores were high, whilst the lowest MDQ scores were observed for a combination of low BAS Fun Seeking and high BIS. However, DYS scores were the stronger predictor of MDQ scores compared to the BAS Fun Seeking and BIS interaction.

Conclusions:

Bipolar-vulnerability is prospectively associated with heightened BAS Dysregulation, as measured by the DYS subscale, similar to prior findings in clinical samples. Further research investigating the longer-term associations between BAS Dysregulation with the development of clinically significant bipolar mood symptoms is required.

Keywords

Behavioural activationBipolar disorderDysregulationHypomanic personalityVulnerability
Type
Original article
Information
European Psychiatry , Volume 44 , July 2017 , pp. 24 - 29
Copyright
Copyright © European Psychiatric Association 2017

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