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A randomized trial to assess the efficacy of a psychoeducational intervention on caregiver burden in schizophrenia

Published online by Cambridge University Press:  23 March 2020

M. Martín-Carrasco ,
P. Fernández-Catalina ,
A.I. Domínguez-Panchón ,
M. Gonçalves-Pereira ,
E. González-Fraile ,
P. Muñoz-Hermoso ,
J. Ballesteros  and
the EDUCA-III group
M. Martín-Carrasco
Affiliation:
Institute of Psychiatric Research, Bilbao, Spain Padre Menni Psychiatric Centre, Pamplona, Spain CIBER Mental HealthSpain
P. Fernández-Catalina
Affiliation:
Psychosocial Rehabilitation Resource (Sisters Hospitallers), Madrid, Spain
A.I. Domínguez-Panchón
Affiliation:
Aita-Menni Hospital, Arrasate-Mondragón, Spain
M. Gonçalves-Pereira
Affiliation:
Clínica Psiquiátrica de S. José (Sisters Hospitallers), Lisboa, Portugal CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Universidade NOVA de Lisboa, Lisboa, Portugal
E. González-Fraile*
Affiliation:
Institute of Psychiatric Research, Bilbao, Spain
P. Muñoz-Hermoso
Affiliation:
Padre Menni Psychiatric Centre, Pamplona, Spain
J. Ballesteros
Affiliation:
University of the Basque Country, UPV/EHU, Leioa, Spain CIBER Mental HealthSpain
*
⁎ Corresponding author. Instituto de Investigaciones Psiquiá tricas, C/Eganã 10, 48010 Bilbao, Spain. Tel.: +34 94 443 4927; fax: +34 94 443 7131. E-mail address:iip@fundacion-iip.org (E. Gonzaález-Fraile).
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Abstract

Background

Patient's relatives usually care for patients with schizophrenia, and as informal caregivers they experience negative consequences. The aim of the EDUCA-III trial is to test the efficacy of a psychoeducational intervention program (PIP) versus standard care to reduce the caregiver burden at post-intervention (4 months), and at follow-up (8 months).

Method

A two-arm, evaluator blind, multicentre, randomized controlled trial. The PIP group had 12 weekly group sessions. The control intervention group had the usual support and standard care. Primary outcomes were change scores since baseline on the Zarit Burden Interview (ZBI) and the Involvement Evaluation Questionnaire (IEQ).

Results

One hundred and nine caregivers were randomized to PIP and 114 to control condition from 23 research sites. The decrease of ZBI scores was significantly higher on the PIP arm at 4 months (mean difference [MD] = −4.33; 95% CI −7.96, −0.71), and at 8 months (MD = −4.46; 95% CI −7.79, −1.13). There were no significant decreases in the IEQ scores (MD at 4 months = −2.80; 95% CI −6.27, 0.67; MD at 8 months = −2.85; 95% CI −6.51, 0.81).

Conclusions

The PIP condition seems to reduce caregiver burden.

Trial registration

ISRCTN32545295.

Keywords

SchizophreniaCaregiversMental healthRandomized controlled trial
Type
Original article
Information
European Psychiatry , Volume 33 , Issue 1 , March 2016 , pp. 9 - 17
Copyright
Copyright © European Psychiatric Association 2016

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