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Subsyndromal symptoms in bipolar disorder

Published online by Cambridge University Press:  13 August 2021

A. Mellouli ,
R. Feki ,
S. Omri ,
N. Smaoui ,
M. Maalej Bouali ,
N. Charfi ,
J. Ben Thabet ,
L. Zouari  and
M. Maalej
A. Mellouli*
Affiliation:
Psychiatry C Department, Hedi chaker university hospital, Sfax, Tunisia
R. Feki
Affiliation:
Psychiatry C Department, Hedi chaker university hospital, sfax, Tunisia
S. Omri
Affiliation:
Psychiatry C Department, Hedi chaker university hospital, sfax, Tunisia
N. Smaoui
Affiliation:
Psychiatry C Department, Hedi chaker university hospital, sfax, Tunisia
M. Maalej Bouali
Affiliation:
Psychiatry C Department, Hedi chaker university hospital, sfax, Tunisia
N. Charfi
Affiliation:
Psychiatry C Department, Hedi chaker university hospital, sfax, Tunisia
J. Ben Thabet
Affiliation:
Psychiatry C Department, Hedi chaker university hospital, sfax, Tunisia
L. Zouari
Affiliation:
Psychiatry C Department, Hedi chaker university hospital, sfax, Tunisia
M. Maalej
Affiliation:
Psychiatry C Department, Hedi chaker university hospital, sfax, Tunisia
*
*Corresponding author.

Abstract

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Introduction

The inter-critical phase in bipolar disorder may contain symptoms that do not meet the diagnostic criteria for a thymic episode. According to studies, these symptoms are common and usually associated with impaired psychosocial and family functioning.

Objectives

Study the subsyndromal symptoms in remitted patients with bipolar disorder, and their functioning repercussions.

Methods

We conducted a cross-sectional, descriptive and analytical study, in the outpatient psychiatry department of the University Hospital in Sfax (Tunisia) among 30 remitted patients with bipolar disorder. We used: the Montgomery And Asberg Depression Rating Scale (MADRS), the Angst Hypomania Questionnaire and the FAST test to assess functioning levels.

Results

The average age of our population was 44.37±15.45 years with a sex ratio (M/F) =0.66. Most of them lived in urban areas (60%) and half of them did not go beyond the primary school level. Most did not have a constant job (76.6%). The average number of previous thymic episodes was 2±1.33 times/year. A quarter of the patients (26.6%) had hypomanic symptoms in the intercritical phase and 20% had depressive symptoms. Hypomanic symptoms were correlated with tobacco use (p=0.035). Depressive symptoms weremore frequent in men (p=0.074). Functioninglevel was lower in subjects living in rural areas (p=0.065).

Conclusions

Our study suggests that residual symptoms were frequent with a significant functional impact. As a result, their identification and management are highly essential to improve the overall functioning of patients with bipolar disorder.

Keywords

bipolar disorderdisease residual minimaldepressive symptomsmanía
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S203 - S204
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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