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Temperament in schizophrenia: a study of the tridimensional personality questionnaire (TPQ)

Published online by Cambridge University Press:  16 April 2020

Andrei Szöke ,
Franck Schürhoff ,
Nathalie Ferhadian ,
Frank Bellivier ,
Frédéric Rouillon  and
Marion Leboyer
Andrei Szöke
Affiliation:
Service de psychiatrie adulte, Hôpital Henri Mondor et Albert Chenevier, 40, rue de Mesly, AP-HP, 94000Créteil, France Inserm U 513, Laboratoire Neurobiologie et Psychiatrie, Faculté de Médecine Henri Mondor, 94000Créteil, France
Franck Schürhoff
Affiliation:
Service de psychiatrie adulte, Hôpital Henri Mondor et Albert Chenevier, 40, rue de Mesly, AP-HP, 94000Créteil, France Inserm U 513, Laboratoire Neurobiologie et Psychiatrie, Faculté de Médecine Henri Mondor, 94000Créteil, France
Nathalie Ferhadian
Affiliation:
Service de psychiatrie adulte, Hôpital Henri Mondor et Albert Chenevier, 40, rue de Mesly, AP-HP, 94000Créteil, France
Frank Bellivier
Affiliation:
Service de psychiatrie adulte, Hôpital Henri Mondor et Albert Chenevier, 40, rue de Mesly, AP-HP, 94000Créteil, France Inserm U 513, Laboratoire Neurobiologie et Psychiatrie, Faculté de Médecine Henri Mondor, 94000Créteil, France
Frédéric Rouillon
Affiliation:
Service de psychiatrie adulte, Hôpital Henri Mondor et Albert Chenevier, 40, rue de Mesly, AP-HP, 94000Créteil, France Inserm U 513, Laboratoire Neurobiologie et Psychiatrie, Faculté de Médecine Henri Mondor, 94000Créteil, France
Marion Leboyer*
Affiliation:
Service de psychiatrie adulte, Hôpital Henri Mondor et Albert Chenevier, 40, rue de Mesly, AP-HP, 94000Créteil, France Inserm U 513, Laboratoire Neurobiologie et Psychiatrie, Faculté de Médecine Henri Mondor, 94000Créteil, France
*
*E-mail address:leboyer@im3.inserm.fr (M. Leboyer).
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Summary

Purpose

The aim of this study was to assess dimensions of temperament as defined by Cloninger’s neurobiological model using the tridimensional personality questionnaire (TPQ) in a sample of consecutively recruited schizophrenic patients.

Subjects and methods

We used the French version of the TPQ to compare 45 stable, euthymic schizophrenic patients with 126 controls with no personal or familial history of psychiatric disorder. After comparison of TPQ scores between groups, we also performed a multivariate analysis to avoid the confounding effects of age, gender, and alcohol and substance use disorder comorbidity.

Results

Harm avoidance (HA) was higher in schizophrenic patients than in controls.

Discussion and conclusion

This replicates and extends the results of previous studies suggesting that schizophrenic patients have high HA and that HA might be a marker for underlying genetic vulnerability to schizophrenia.

Keywords

TemperamentSchizophreniaTridimensional personality questionnaire
Type
Original article
Information
European Psychiatry , Volume 17 , Issue 7 , November 2002 , pp. 379 - 383
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2002

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