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A steep cline for mitochondrial DNA in Danish mice

Published online by Cambridge University Press:  14 April 2009

F. Vanlerberghe ,
P. Boursot ,
J. T. Nielsen  and
F. Bonhomme
F. Vanlerberghe
Affiliation:
Laboratoire de génétique, Institut des Sciences de I'Evolution(UA. CNRS 327), U.S.T.L., Place E. Batailon, 34060 Montpellier CedexFrance
P. Boursot*
Affiliation:
Laboratoire de génétique, Institut des Sciences de I'Evolution(UA. CNRS 327), U.S.T.L., Place E. Batailon, 34060 Montpellier CedexFrance
J. T. Nielsen
Affiliation:
Institute of Molecular Biology and Plant Physiology, University of Aarhus, Aarhus Denmark
F. Bonhomme
Affiliation:
Laboratoire de génétique, Institut des Sciences de I'Evolution(UA. CNRS 327), U.S.T.L., Place E. Batailon, 34060 Montpellier CedexFrance
*
* Corresponding author
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One hundred and ninety-eight mice trapped along a south–north transect through the Danish hybrid zone between Mus musculus domesticus and M. m. musculus were typed for mitochondrial DNA (mtDNA), the Y chromosome and ten autosomal loci encoding diagnostic proteins. The southern (domesticus) populations display two mtDNA variants (S1 and S2) and the northern (musculus) have a third mtDNA variant (N) of domesticus origin. Across the hybrid zone defined by ten autosomal loci, there is a steep dine between the southern and northern types of mtDNA. As well as confirming an earlier finding that Danish musculus all have a domesticus mtDNA (Ferris et al. 1983a, & b), our results show that this mtDNA takeover is not the result of a persistent mitochondrial gene flow between the two subspecies. While the coincident dines for the ten autosomal loci and the abrupt dine for the Y chromosome can be explained by selection, it is less likely to be the case for the mtDNA exchanges. We discuss the possible role of sex-linked migration and genetic drift to account for the distribution of the mitochondrial variants.

Type
Research Article
Information
Genetics Research , Volume 52 , Issue 3 , December 1988 , pp. 185 - 193
Copyright
Copyright © Cambridge University Press 1988

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