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A Pseudo-outbreak of Aspergillosis at a Tertiary Care Hospital: Thinking Beyond the Infection Control Risk Assessment

Published online by Cambridge University Press:  11 October 2016

Michelle Doll*
Affiliation:
Virginia Commonwealth University Medical Center, Richmond, Virginia
Michael Anne Preas
Affiliation:
University of Maryland Medical Center, Baltimore, Maryland
J. Kristie Johnson
Affiliation:
University of Maryland School of Medicine, Baltimore, Maryland
Clifford Mitchell
Affiliation:
Maryland Department of Health and Mental Hygiene, Baltimore, Maryland
Brenda Roup
Affiliation:
Maryland Department of Health and Mental Hygiene, Baltimore, Maryland
Lucy Wilson
Affiliation:
Maryland Department of Health and Mental Hygiene, Baltimore, Maryland
Christine Carothers
Affiliation:
University of Maryland Medical Center, Baltimore, Maryland
Grace Nkonge
Affiliation:
University of Maryland Medical Center, Baltimore, Maryland
Surbhi Leekha
Affiliation:
University of Maryland School of Medicine, Baltimore, Maryland
*
Address correspondence to Michelle Doll, MD, MPH, Virginia Commonwealth University Health System, 1300 East Marshall Street, North Hospital, 2nd Floor Rm 2-100, P.O. Box 980019, Richmond, VA 23298-0019 (Michelle.Doll@vcuhealth.org).

Abstract

In the modern era of carefully monitored renovations, construction-related Aspergillus outbreaks have decreased. We investigated an increase in clinical cultures growing Aspergillus species, determining that contamination of the mycology lab caused a pseudo-outbreak. A major construction site was appropriately sealed, but unrecognized staff traffic may have facilitated laboratory contamination.

Infect Control Hosp Epidemiol 2016;1–4

Type
Concise Communications
Copyright
© 2016 by The Society for Healthcare Epidemiology of America. All rights reserved 

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References

REFERENCES

1. Hahn, T, Cummings, KM, Michalek, AM, Lipman, BJ, Segal, BH, McCarthy, PL Jr. Efficacy of high-efficiency particulate air filtration in preventing aspergillosis in immunocompromised patients with hematologic malignancies. Infect Control Hosp Epidemiol 2002;23:525531.CrossRefGoogle ScholarPubMed
2. Oren, I, Haddad, N, Finkelstein, R, Rowe, JM. Invasive pulmonary aspergillosis in neutropenic patients during hospital construction: before and after chemoprophylaxis and institution of HEPA filters. Am J Hematol 2001;66:257262.Google Scholar
3. Chang, CC, Cheng, AC, Devitt, B, et al. Successful control of an outbreak of invasive aspergillosis in a regional haematology unit during hospital construction works. J Hosp Infect 2008;69:3338.Google Scholar
4. Freeman, J, Rogers, K, Roberts, S. Pseudo-outbreak of aspergillus keratitis following construction in an ophthalmology ward. J Hosp Infect 2007;67:104105.Google Scholar
5. De Pauw, B, Walsh, TJ, Donnelly, JP, et al. Revised definitions of invasive fungal disease from the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group (EORTC/MSG) Consensus Group. Clin Infect Dis 2008;46:18131821.Google Scholar
6. American Institute of Architects. Guidelines for Design and Construction of Hospital and Health Care Facilities. 2006 ed. Washington, DC: American Institute of Architects; 2006.Google Scholar
7. Anderson, AA. New sampler for the collection, sizing and enumeration of viable airborne particles. J Bacteriol 1958;76:471484.Google Scholar
8. Lutz, BD, Jin, J, Rinaldi, MG, Wickes, BL, Huycke, MM. Outbreak of invasive aspergillus infection in surgical patients, associated with a contaminated air-handling system. Clin Infect Dis 2003;37:786793.CrossRefGoogle ScholarPubMed
9. Balajee, SA, de Valk, HA, Lasker, BA, Meis, JF, Klaassen, CH. Utility of a microsatellite assay for identifying clonally related outbreak isolates of aspergillus fumigatus. J Microbiol Meth 2008;73:252256.CrossRefGoogle ScholarPubMed