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Activity of Disinfectants Against Vancomycin-Resistant Enterococcus faecium

Published online by Cambridge University Press:  02 January 2015

Abstract

Vancomycin-resistant enterococci (VRE) often contaminate the hospital environment. We examined the activity of commonly used disinfectants against eight strains of VRE, using a quantitative suspension test method. Isopropyl alcohol and sodium hypochlorite were highly effective. Hydrogen peroxide was ineffective for all strains. After 10 minutes of incubation (the manufacturers' recommended time of exposure), three phenolic and three quaternary ammonium compounds also were highly effective. After 3 minutes of exposure, however, occasional failures did occur. With the exception of 3% hydrogen peroxide, most disinfectants appear to be active against VRE.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1997

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References

1. Centers for Disease Control and Prevention. Nosocomial enterococci resistant to vancomycin–United States, 1989-1993. MMWR 1993;42:597599.Google Scholar
2. Livornese, LL Jr, Dias, S, Samel, C, et al. Hospital-acquired infection with vancomycin-resistant Enterococcus faecium transmitted by electronic thermometers. Ann Intern Med 1992;117:112116.CrossRefGoogle ScholarPubMed
3. Boyce, JM, Opal, SM, Chow, JW, et al. Outbreak of multidrugresistant Enterococcus faecium with transferable vanB class vancomycin resistance. J Clin Microbiol 1994;32:11481153.CrossRefGoogle Scholar
4. Edmund, MB, Ober, JS, Weinbaum, DL, et al. Vancomycin-resistant Enterococcus faecium bacteremia: risk factors for infection. Clin Infect Dis 1995;20:11261133.CrossRefGoogle Scholar
5. Morris, JG, Shay, DK, Hebden, JN, et al. Enterococci resistant to multiple antimicrobial agents, including vancomycin. Ann Intern Med 1995;123:250259.CrossRefGoogle ScholarPubMed
6. Cremieux, A, Fleurette, J. Methods of testing disinfectants. In: Block, SS, ed. Disinfection, Sterilization and Preservation. 4th ed. Philadelphia, PA: Lea & Febiger; 1991:10091027.Google Scholar
7. Beloian, A. Disinfectants. In: Helrich, K, ed. Official Methods of Analysis of the Association of Official Analytical Chemists. 15th ed. Arlington, VA: Association of Official Analytical Chemists, Inc; 1990:133146.Google Scholar
8. Landman, D, Quale, JM, Oydna, E, et al. Comparison of five selective media for identifying fecal carriage of vancomycin-resistant enterococci. J Clin Microbiol 1996;34:751752.CrossRefGoogle ScholarPubMed
9. National Committee for Clinical Laboratory Standards. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically. Approved standard M7-A3. Villanova, PA: NCCLS; 1993.Google Scholar
10. Hospital Infection Control Practices Advisory Committee. Recommendations for preventing the spread of vancomycin resistance. Infect Control Hosp Epidemiol 1995;16:105113.CrossRefGoogle Scholar
11. Wade, JJ, Desai, N, Casewell, MW. Hygienic hand disinfection for the removal of epidemic vancomycin-resistant Enterococcus faecium and gentamicin-resistant Enterobacter cloacae . J Hosp Infect 1991;18:211218.CrossRefGoogle ScholarPubMed
12. Rutala, WA. APIC guidelines for selection and use of disinfectants. Am J Infect Control 1980;18:99117.CrossRefGoogle Scholar