Hostname: page-component-cd9895bd7-dzt6s Total loading time: 0 Render date: 2024-12-28T20:22:07.157Z Has data issue: false hasContentIssue false

Comparison of Antibiotic Susceptibility Patterns of Bacterial Isolates Based on Time From Hospitalization and Culture Source: Implications for Hospital Antibiograms

Published online by Cambridge University Press:  13 November 2015

Yaakov Dickstein*
Affiliation:
Division of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel
Yuval Geffen
Affiliation:
Medical Microbiology Laboratory, Rambam Health Care Campus, Haifa, Israel
Leonard Leibovici
Affiliation:
Medicine E, Rabin Medical Center, Beilinson Hospital, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
Mical Paul
Affiliation:
Division of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel
*
Address correspondence to Dr. Yaakov Dickstein, Division of Infectious Diseases, Rambam Health Care Campus, HaAliya HaShniya St. 8, Haifa, Israel 3109601 (y_dickstein@rambam.health.gov.il).

Abstract

We assessed the effects of time from hospitalization and culture source on bacterial susceptibility profiles. Increasing resistance correlated with increasing time from hospitalization for all bacterial groups, with 7 days in hospital representing the best time point for dichotomizing susceptibility rates rather than 48 hours. Antibiograms based on isolates from any source best represented susceptibility profiles.

Infect. Control Hosp. Epidemiol. 2016;37(2):212–214

Type
Concise Communications
Copyright
© 2015 by The Society for Healthcare Epidemiology of America. All rights reserved 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

PREVIOUS PRESENTATION. The data from this article was presented as a poster at the 2015 Conference of the Israeli Society of Infectious Diseases.

References

1. Hindler, JF, Stelling, J. Analysis and presentation of cumulative antibiograms: a new consensus guideline from the Clinical and Laboratory Standards Institute. Clin Infect Dis 2007;44:867873.Google Scholar
2. Bantar, C, Alcazar, G, Franco, D, et al. Are laboratory-based antibiograms reliable to guide the selection of empirical antimicrobial treatments in patients with hospital-acquired infections? J Antimicrob Chemother 2007;59:140143.CrossRefGoogle ScholarPubMed
3. Analysis and Presentation of Cumulative Antimicrobial Susceptibility Test Data. 3rd ed. (CLSI publication M39-A3). Wayne, PA: Clinical and Laboratory Standards Institute, 2009.Google Scholar
4. Magiorakos, AP, Srinivasan, A, Carey, RB, et al. Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Clin Microbiol Infect 2012;18:268281.Google Scholar
5. Garner, JS, Jarvis, WR, Emori, TG, Horan, TC, Hughes, JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988;16:128140.Google Scholar
6. Cardoso, T, Almeida, M, Friedman, ND, et al. Classification of healthcare-associated infection: a systematic review 10 years after the first proposal. BMC Med 2014;12:40.CrossRefGoogle ScholarPubMed
7. Kuster, SP, Ruef, C, Zbinden, R, et al. Stratification of cumulative antibiograms in hospitals for hospital unit, specimen type, isolate sequence and duration of hospital stay. J Antimicrob Chemother 2008;62:14511461.Google Scholar
8. Leibovici, L, Schønheyder, H, Pitlik, SD, Samra, Z, Møller, JK. Bacteraemia caused by hospital-type micro-organisms during hospital stay. J Hosp Infect 2000;44:3136.CrossRefGoogle ScholarPubMed
9. Draper, HM, Farland, JB, Heidel, RE, May, LS, Suda, KJ. Comparison of bacteria isolated from emergency department patients versus hospitalized patients. Am J Health Syst Pharm 2013;70:21242128.Google Scholar
10. Hombach, M, Bloemberg, GV, Böttger, EC. Effects of clinical breakpoint changes in CLSI guidelines 2010/11 and EUCAST guidelines 2011 on antibiotic susceptibility test reporting of Gram-negative bacilli. J Antimicrob Chemother 2012;67:622632.Google Scholar