Hostname: page-component-6bf8c574d5-pdxrj Total loading time: 0 Render date: 2025-03-04T04:25:40.529Z Has data issue: false hasContentIssue false
  • English
  • Français

Development and Application of an Antibiotic Spectrum Index for Benchmarking Antibiotic Selection Patterns Across Hospitals

Published online by Cambridge University Press:  31 May 2017

Jeffrey S. Gerber ,
Adam L. Hersh ,
Matthew P. Kronman ,
Jason G. Newland ,
Rachael K. Ross  and
Talene A. Metjian
Jeffrey S. Gerber*
Affiliation:
Division of Infectious Diseases and The Center for Pediatric Clinical Effectiveness, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
Adam L. Hersh
Affiliation:
Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Utah, Salt Lake City, Utah
Matthew P. Kronman
Affiliation:
Division of Infectious Diseases, Seattle Children’s Hospital, Seattle, Washington
Jason G. Newland
Affiliation:
Division of Pediatric Infectious Diseases, Washington University, St. Louis, Missouri
Rachael K. Ross
Affiliation:
Division of Infectious Diseases and The Center for Pediatric Clinical Effectiveness, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
Talene A. Metjian
Affiliation:
Antimicrobial Stewardship Program, Office of Safety and Medical Operations, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania.
*
Address correspondence to Jeffrey S. Gerber, MD, PhD, Division of Infectious Diseases, The Children’s Hospital of Philadelphia, CHOP North, Suite 1518, Philadelphia, PA 19104 (gerberj@email.chop.edu).
Get access Rights & Permissions [Opens in a new window]

Abstract

Standard metrics for antimicrobial use consider volume but not spectrum of antimicrobial prescribing. We developed an antibiotic spectrum index (ASI) to classify commonly used antibiotics based on activity against important pathogens. The application of this index to hospital antibiotic use reveals how this tool enhances current antimicrobial stewardship metrics.

Infect Control Hosp Epidemiol 2017;38:993–997

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 38 , Issue 8 , August 2017 , pp. 993 - 997
Copyright
© 2017 by The Society for Healthcare Epidemiology of America. All rights reserved 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

PREVIOUS PRESENTATION: The work reported here was presented at ID Week 2014 on October 10, 2014, in Philadelphia, Pennsylvania.

References

REFERENCES

1. Policy statement on antimicrobial stewardship by the Society for Healthcare Epidemiology of America (SHEA), the Infectious Diseases Society of America (IDSA), and the Pediatric Infectious Diseases Society (PIDS). Infect Control Hosp Epidemiol 2012;33:322–327.CrossRefGoogle Scholar
2. Barlam, TF, Cosgrove, SE, Abbo, LM, et al. Implementing an antibiotic stewardship program: guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America. Clin Infect Dis 2016;62:e51–e77.CrossRefGoogle Scholar
3. Moehring, RW, Anderson, DJ, Cochran, RL, Hicks, LA, Srinivasan, A, Dodds Ashley, ES. Expert consensus on metrics to assess the impact of patient-level antimicrobial stewardship interventions in acute-care settings. Clin Infect Dis 2017;64:377–383.CrossRefGoogle ScholarPubMed
4. Gerber, JS, Kronman, MP, Ross, RK, et al. Identifying targets for antimicrobial stewardship in children’s hospitals. Infect Control Hosp Epidemiol 2013;34:1252–1258.CrossRefGoogle ScholarPubMed
5. Ross, RK, Hersh, AL, Kronman, MP, et al. Impact of Infectious Diseases Society of America/Pediatric Infectious Diseases Society guidelines on treatment of community-acquired pneumonia in hospitalized children. Clin Infect Dis 2014;58:834–838.CrossRefGoogle Scholar
6. Newman, RE, Hedican, EB, Herigon, JC, Williams, DD, Williams, AR, Newland, JG. Impact of a guideline on management of children hospitalized with community-acquired pneumonia. Pediatrics 2012;129:e597–e604.CrossRefGoogle ScholarPubMed
7. Fitzmaurice, GM, Laird, NM. Applied Longitudinal Analysis. 2nd ed. Hoboken, NJ: Wiley & Sons; 2011.CrossRefGoogle Scholar
8. Madaras-Kelly, K, Jones, M, Remington, R, Hill, N, Huttner, B, Samore, M. Development of an antibiotic spectrum score based on veterans affairs culture and susceptibility data for the purpose of measuring antibiotic de-escalation: a modified Delphi approach. Infect Control Hosp Epidemiol 2014;35:1103–1113.CrossRefGoogle ScholarPubMed
9. Stenehjem, E, Hersh, AL, Sheng, X, et al. Antibiotic use in small community hospitals. Clin Infect Dis 2016;63:1273–1280.CrossRefGoogle ScholarPubMed
10. Antimicrobial use and resistance (AUR) module. Centers for Disease Control and Prevention website. https://www.cdc.gov/nhsn/PDFs/pscManual/11pscAURcurrent.pdf. Published 2017. Accessed April 1, 2017.Google Scholar