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Development and implementation of a short duration antibiotic therapy algorithm for uncomplicated gram-negative bloodstream infections

Published online by Cambridge University Press:  04 May 2021

Esther Y. Bae Open the ORCID record for Esther Y. Bae [Opens in a new window] ,
Kathryn Dzintars ,
Fidelia Bernice ,
Pranita D. Tamma ,
Sara E. Cosgrove  and
Edina Avdic
Esther Y. Bae*
Affiliation:
Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland
Kathryn Dzintars
Affiliation:
Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland
Fidelia Bernice
Affiliation:
Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland
Pranita D. Tamma
Affiliation:
Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland
Sara E. Cosgrove
Affiliation:
Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland
Edina Avdic
Affiliation:
Department of Pharmacy, The Johns Hopkins Hospital, Baltimore, Maryland
*
Author for correspondence: Esther Y. Bae, E-mail: esther.bae@utsouthwestern.edu
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Abstract

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Type
Research Brief
Information
Infection Control & Hospital Epidemiology , Volume 42 , Issue 9 , September 2021 , pp. 1136 - 1138
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Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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Footnotes

PREVIOUS PRESENTATION. These data were presented as a poster at IDWeek 2020 on October 22, 2020, conducted virtually.

References

Yahav, D, Franceschini, E, Koppel, F, et al. Seven versus 14 days of antibiotic therapy for uncomplicated gram-negative bacteremia: a noninferiority randomized controlled trial. Clin Infect Dis 2019;69:1091–1098.CrossRefGoogle ScholarPubMed
Chotiprasitsakul, D, Han, JH, Cosgrove, SE, et al. Comparing the outcomes of adults with enterobacteriaceae bacteremia receiving short-course versus prolonged-course antibiotic therapy in a multicenter, propensity score-matched cohort. Clin Infect Dis 2018;66:172–177.CrossRefGoogle Scholar
Von dach, E, Albrich, WC, Brunel, AS, et al. Effect of C-reactive protein-guided antibiotic treatment duration, 7-day treatment, or 14-day treatment on 30-day clinical failure rate in patients with uncomplicated gram-negative bacteremia: a randomized clinical trial. JAMA 2020;323:2160–2169.CrossRefGoogle ScholarPubMed
Corey, GR, Stryjewski, ME, Everts, RJ. Short-course therapy for bloodstream infections in immunocompetent adults. Int J Antimicrob Agents 2009;34 suppl 4:S47–S51.CrossRefGoogle Scholar
Swamy, S, Sharma, R. Duration of treatment of gram-negative bacteremia: are shorter courses of antimicrobial therapy feasible? Infect Dis Clin Pract 2016;24:155–160.CrossRefGoogle Scholar
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