Hostname: page-component-cd9895bd7-q99xh Total loading time: 0 Render date: 2024-12-28T04:27:57.130Z Has data issue: false hasContentIssue false
  • English
  • Français

The Effect of a Hospital-Wide Urine Culture Screening Intervention on the Incidence of Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella Species

Part of: BARRY FARR AWARD RECIPIENTS

Published online by Cambridge University Press:  02 January 2015

Jennifer H. Han ,
Warren B. Bilker ,
Irving Nachamkin ,
Theoklis E. Zaoutis ,
Susan E. Coffin ,
Darren R. Linkin ,
Baofeng Hu ,
Pam Tolomeo ,
Neil O. Fishman  and
Ebbing Lautenbach
Jennifer H. Han*
Affiliation:
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Warren B. Bilker
Affiliation:
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Irving Nachamkin
Affiliation:
Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Theoklis E. Zaoutis
Affiliation:
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Division of Infectious Diseases and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Susan E. Coffin
Affiliation:
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Division of Infectious Diseases and Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Darren R. Linkin
Affiliation:
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania
Baofeng Hu
Affiliation:
Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Pam Tolomeo
Affiliation:
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Neil O. Fishman
Affiliation:
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
Ebbing Lautenbach
Affiliation:
Division of Infectious Diseases, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
*
Division of Infectious Diseases, Department of Medicine, Hospital of the University of Pennsylvania, 811 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 (jennifer.han@uphs.upenn.edu)
Get access Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Original Article
Information
Infection Control & Hospital Epidemiology , Volume 34 , Issue 11 , November 2013 , pp. 1160 - 1166
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.National Nosocomial Infections Surveillance System. National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control 2004;32:470–485.Google Scholar
2.Neuhauser, MM, Weinstein, RA, Rydman, R, Danziger, LH, Karam, G, Quinn, JRAntibiotic resistance among gram-negative bacilli in US intensive care units: implications for fluoroquinolone use. JAMA 2003;289:885–888.Google Scholar
3.Lautenbach, E, Patel, JB, Bilker, WB, Edelstein, PH, Fishman, NO. Extended-spectrum β-lactamase-produring Escherichia coli and Klebsiella pneumoniae, risk factors for infection and impact of resistance on outcomes. Clin Infect Dis 2001;32:1162–1171.Google Scholar
4.Schwaber, MJ, Navon-Venezia, S, Kaye, KS, Ben-Ami, R, Schwartz, D, Carmeli, Y. Clinical and economic impact of bacteremia with extended-spectrum-β-lactamase-producing Enterobacteriaceae. Antimicrob Agents Chemother 2006;50:1257–1262.Google Scholar
5.Lee, SY, Kotapati, S, Kuti, JL, Nightingale, CH, Nicolau, DP. Impact of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella species on clinical outcomes and hospital costs: a matched cohort study. Infect Control Hosp Epidemiol 2006;27:1226–1232.CrossRefGoogle ScholarPubMed
6.Goddard, S, Muller, MP. The efficacy of infection control interventions in reducing the incidence of extended-spectrum β-lactamase-producing Enterobacteriaceae in the nonoutbreak setting: a systematic review. Am J Infect Control 2011;39:599–601.CrossRefGoogle ScholarPubMed
7.Siegel, JD, Rhinehart, E, Jackson, M, Chiarello, L. Management of multidrug-resistant organisms in health care settings, 2006. Am J Infect Control 2007;35:S165–S193.Google Scholar
8.Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. Wayne, PA: CLSI, 2010. CLSI document M100-S20.Google Scholar
9.Harris, AD, Bradham, DD, Baumgarten, M, Zuckerman, IH, Fink, JC, Perencevich, EN. The use and interpretation of quasi-experimental studies in infectious diseases. Clin Infect Dis 2004;38:1586–1591.Google Scholar
10.Harris, AD, Lautenbach, E, Perencevich, E. A systematic review of quasi-experimental study designs in the fields of infection control and antibiotic resistance. Clin Infect Dis 2005;41:77–82.Google Scholar
11.Valverde, A, Coque, TM, Sánchez-Moreno, MP, Rollán, A, Baquero, F, Canton, R. Dramatic increase in prevalence of fecal carriage of extended-spectrum β-lactamase-producing Enterobacteriaceae during nonoutbreak situations in Spain. J Clin Microbiol 2004;42:4769–4775.Google Scholar
12.Ling, TK, Tam, PC, Liu, ZK, Cheng, AF. Evaluation of VITEK 2 rapid identification and susceptibility testing system against gram-negative clinical isolates. J Clin Microbiol 2001;39:2964–2966.Google Scholar
13.Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. Wayne, PA: CLSI, 2008. CLSI document M100-S18.Google Scholar
14.Lautenbach, E, Metlay, JP, Mao, X, et al. The prevalence of fluoroquinolone resistance mechanisms in colonizing Escherichia coli isolates recovered from hospitalized patients. Clin Infect Dis 2010;51:280–285.Google Scholar
15.Oethinger, M, Conrad, S, Kaifel, K, et al. Molecular epidemiology of fluoroquinolone-resistant Escherichia coli bloodstream isolates from patients admitted to European cancer centers. Antimicrob Agents Chemother 1996;40:387–392.Google Scholar
16.Matowe, LK, Leister, CA, Crivera, C, Korth-Bradley, JM. Interrupted time series analysis in clinical research. Ann Pharmacother 2003;37:1110–1116.Google Scholar
17.Conterno, LO, Shymanski, J, Ramotar, K, Toye, B, Zvonar, R, Roth, V. Impact and cost of infection control measures to reduce nosocomial transmission of extended-spectrum β-lactamase-producing organisms in a non-outbreak setting. J Hosp Infect 2007;65:354–360.Google Scholar
18.Johnson, PD, Martin, R, Burreil, LJ, et al. Efficacy of an alcohol/Chlorhexidine hand hygiene program in a hospital with high rates of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection. Med J Aust 2005;183:509–514.Google Scholar
19.Souweine, B, Traore, O, Aublet-Cuvelier, B, et al. Role of infection control measures in limiting morbidity associated with multi-resistant organisms in critically ill patients. J Hosp Infect 2000; 45:107–116.CrossRefGoogle ScholarPubMed
20.Soulier, A, Barbut, F, Ollivier, JM, Petit, JC, Lienhart, A. Decreased transmission of Enterobacteriaceae with extended-spectrum β-lactamases in an intensive care unit by nursing reorganization. J Hosp Infect 1995;31:89–97.Google Scholar
21.Pitout, JDD, Nordmann, P, Laupland, KB, Poirel, L. Emergence of Enterobacteriaceae producing extended-spectrum β-lactamases (ESBLs) in the community. J Antimicrob Chemother 2005;56:52–59.Google Scholar
22.Doi, Y, Adams, J, O'Keefe, A, Quereshi, Z, Ewan, L, Paterson, DL. Community-acquired extended-spectrum β-lactamase producers, United States. Emerg Infect Dis 2007;13:1121–1123.Google Scholar
23.Rodriguez-Baño, J, Alcalá, JC, Cisneros, JM, et al. Community infections caused by extended-spectrum β-lactamase-producing Escherichia coli. Arch Intern Med 2008;168:1897–1902.Google Scholar
24.Harris, AD, Kotetishvili, M, Shurland, S, et al. How important is patient-to-patient transmission in extended-spectrum β-lactamase Escherichia coli acquisition. Am J Infect Control 2007;35: 97–101.Google Scholar
25.Tschudin-Sutter, S, Frei, R, Dangel, M, Stranden, A, Widmer, AR, Rate of transmission of extended-spectrum betaβ-lactamase-pro-ducing Enterobacteriaceae without contact isolation. Clin Infect Dis 2012;55:1505–1511.Google Scholar
26.Harris, AD, Perencevich, EN, Johnson, JK, et al. Patient-to-patient transmission is important in extended-spectrum β-lactamase-producing Klebsiella pneumoniae acquisition. Clin Infect Dis 2007;45:1347–1350.Google Scholar
27.Hilty, M, Betsch, BY, Bögli-Stuber, K, et al. Transmission dynamics of extended-spectrum β-lactamase-producing Enterobacteriaceae in the tertiary care hospital and the household setting. Clin Infect Dis 2012;55:967–975.Google Scholar
28.Doi, Y, Park, YS, Rivera, JI, et al. Community-associated extended-spectrum |Sβ-lactamase-producing Escherichia coli infection in the United States. Clin Infect Dis 2013;56:641–648.Google Scholar