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How Does a Photocatalytic Antimicrobial Coating Affect Environmental Bioburden in Hospitals?

Published online by Cambridge University Press:  12 February 2018

Matthew Reid ,
Vanessa Whatley ,
Emma Spooner ,
Alan M. Nevill ,
Michael Cooper ,
Jeremy J. Ramsden  and
Stephanie J. Dancer
Matthew Reid
Affiliation:
New Cross Hospital, The Royal Wolverhampton NHS Trust, England
Vanessa Whatley
Affiliation:
New Cross Hospital, The Royal Wolverhampton NHS Trust, England
Emma Spooner
Affiliation:
New Cross Hospital, The Royal Wolverhampton NHS Trust, England
Alan M. Nevill
Affiliation:
Faculty of Education, Health and Wellbeing, University of Wolverhampton, England
Michael Cooper
Affiliation:
New Cross Hospital, The Royal Wolverhampton NHS Trust, England
Jeremy J. Ramsden*
Affiliation:
Clore Laboratory, University of Buckingham, England
Stephanie J. Dancer
Affiliation:
Department of Microbiology, Hairmyres Hospital, NHS Lanarkshire, Scotland School of Applied Sciences, Edinburgh Napier University, Edinburgh, Scotland
*
Address correspondence to Prof. J. J. Ramsden, University of Buckingham, MK18 1EG, UK (jeremy.ramsden@buckingham.ac.uk).
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Abstract

BACKGROUND

The healthcare environment is recognized as a source for healthcare-acquired infection. Because cleaning practices are often erratic and always intermittent, we hypothesize that continuously antimicrobial surfaces offer superior control of surface bioburden.

OBJECTIVE

To evaluate the impact of a photocatalytic antimicrobial coating at near-patient, high-touch sites in a hospital ward.

SETTING

The study took place in 2 acute-care wards in a large acute-care hospital.

METHODS

A titanium dioxide-based photocatalytic coating was sprayed onto 6 surfaces in a 4-bed bay in a ward and compared under normal illumination against the same surfaces in an untreated ward: right and left bed rails, bed control, bedside locker, overbed table, and bed footboard. Using standardized methods, the overall microbial burden and presence of an indicator pathogen (Staphylococcus aureus) were assessed biweekly for 12 weeks.

RESULTS

Treated surfaces demonstrated significantly lower microbial burden than control sites, and the difference increased between treated and untreated surfaces during the study. Hygiene failures (>2.5 colony-forming units [CFU]/cm2) increased 2.6% per day for control surfaces (odds ratio [OR], 1.026; 95% confidence interval [CI], 1.009–1.043; P=.003) but declined 2.5% per day for treated surfaces (OR, 0.95; 95% CI, 0.925–0.977; P<.001). We detected no significant difference between coated and control surfaces regarding S. aureus contamination.

CONCLUSION

Photocatalytic coatings reduced the bioburden of high-risk surfaces in the healthcare environment. Treated surfaces became steadily cleaner, while untreated surfaces accumulated bioburden. This evaluation encourages a larger-scale investigation to ascertain whether the observed environmental amelioration has an effect on healthcare-acquired infection.

Infect Control Hosp Epidemiol 2018;39:398–404

Type
Original Articles
Information
Infection Control & Hospital Epidemiology , Volume 39 , Issue 4 , April 2018 , pp. 398 - 404
Copyright
© 2018 by The Society for Healthcare Epidemiology of America. All rights reserved 

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