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Methicillin-Resistant Staphylococcus aureus Control: We Didn't Start the Fire, but It's Time to Put It Out

Published online by Cambridge University Press:  21 June 2016

Carlene A. Muto*
Affiliation:
Division of Hospital Epidemiology and Infection Control, University of Pittsburgh Medical Center, Presbyterian Campus, and the Infectious Diseases Epidemiology Research Unit, University of Pittsburgh School of Medicine and Graduate School of Public Health, Pittsburgh, Pennsylvania
*
University of Pittsburgh Medical Center (UPMC-P), 1215 Kaufmann Building, Pittsburgh, PA 15213 (mutoca@msx.upmc.edu)
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Abstract

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Type
Editorial
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2006

References

1.Centers for Disease Control and Prevention. Proportion of healthcare-acquired S. aureus infections resistant to oxacillin (MRSA) among ICU patients, 1989-2003. Vol. 2004. Available at: http://www.cdc.gov/ncidod/dhqp/ar_mrsa.html. Accessed January 25, 2006.Google Scholar
2.Centers for Disease Control and Prevention. National Nosocomial Infections Surveillance (NNIS) system report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control 2004; 32:470485.Google Scholar
3.Centers for Disease Control and Prevention. Campaign to prevent antimicrobial resistance in healthcare settings: why a campaign? 2001. Available at: http://www.cdc.gov/drugresistance/healthcare/problem.htm. Accessed January 27, 2006.Google Scholar
4.Cosgrove, SE, Sakoulas, G, Perencevich, EN, Schwaber, MJ, Karchmer, AW, Carmeli, Y. Comparsion of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bactermia: a meta-analysis. Clin Infect Dis 2003; 36:5359.Google Scholar
5.Engemann, J, Carmeli, Y, Cosgrove, SE, et al. Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infections. Clin Infect Dis 2003; 36: 592598.Google Scholar
6.Centers for Disease Control and Prevention (CDC). Vancomycin-resistant Staphylococcus aureus—New York, 2004. MMWR Morb Mortal Wkly Rep 2004; 53:322323.Google Scholar
7.Muto, CA. Why are antibiotic-resistant nosocomial infections spiraling out of control? Infect Control Hosp Epidemiol 2005; 26:1012.Google Scholar
8.Muto, CA, Jernigan, JA, Ostrowksy, BE, et al. SHEA Guideline for preventing nosocomial transmission of multidrug-resistant strains of Staphylococcus aureus and Enterococcus. Infect Control Hosp Epidemiol 2003; 24:362386.CrossRefGoogle ScholarPubMed
9.Lucet, JC, Chevert, S, Durand-Zaleski, I, Chastang, C, Regnier, B. Multi-center Study Group. Prevalence and risk factors for carriage of methicillin-resistant Staphylococcus aureus at admission to the intensive care unit: results of a multicenter study. Arch Intern Med 2003; 163:181188.Google Scholar
10.Boyce, JM, Havill, NL, Kohan, C, Dumigan, DG, Ligri, CE. Do infection control measures work for methicillin-resistant Staphylococcus aureus? Infect Control Hosp Epidemiol 2004; 25:395401.Google Scholar
11.Salgado, CD, Farr, BM. What proportion of hospital patients colonized with methicillin-resistant Staphylococcus aureus are identified by clinical microbiological cultures? Infect Control Hosp Epidemiol 2006; 27:116121 (in this issue).Google Scholar
12.Eveillard, M, de Lassence, A, Lancien, E, Barnaud, G, Ricard, JD, Joly-Guillou, ML. Evaluation of a strategy of screening multiple anatomical sites for methicillin-resistant Staphylococcus aureus at admission to a teaching hospital. Infect Control Hosp Epidemiol 2006; 27:181184 (in this issue).CrossRefGoogle ScholarPubMed
13.Sandri, AM, Dalarosa, MG, de Alcântara, LR, da Silva Elias, L, Zavascki, AP. Reduction in incidence of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection in an intensive care unit: role of treatment with mupirocin ointment and chlorhexidine baths for nasal carriers of MRSA. Infect Control Hosp Epidemiol 2006; 27:185187 (in this issue).Google Scholar
14.Lucet, JC, Grenet, K, Armond-Lefevre, L, et al. High prevalence of carriage of methicillin-resistant Staphylococcus aureus at hospital admission in elderly patients: implications for infection control strategies. Infect Control Hosp Epidemiol 2005; 26:121126.Google Scholar
15.Goldstein, FW, Acar, JF. Epidemiology of quinolone resistance: Europe and North and South America. Drugs 1995; 49:3642.Google Scholar
16.Safdar, N, Narans, L, Gordon, B, Maki, DG. Comparison of culture screening methods for detection of nasal carriage of methicillin-resistant Staphylococcus aureus: a prospective study comparing 32 methods. J Clin Microbiol 2003; 41:31633166.Google Scholar
17.Blair, EB, Emerson, JS, Tull, AH. A new medium, salt mannitol plasma agar, for the isolation of Staphylococcus aureus. Am J Clin Pathol 1967; 47:3039.Google Scholar
18.Chapman, GH. The significance of sodium chloride in studies of staphylococci. J Bacteriol 1945; 50:201203.Google Scholar
19.La Zonby, JG, Starzyk, MJ. Screening method for recovery of methicillin-resistant Staphylococcus aureus from primary plates. J Clin Microbiol 1986; 24:186188.CrossRefGoogle ScholarPubMed
20.Merlino, J, Gill, R, Robertson, GJ. Application of lipovitellin-salt-mannitol agar for screening, isolation, and presumptive identification of Staphylococcus aureus in a teaching hospital. J Clin Microbiol 1996; 34:30123015.CrossRefGoogle ScholarPubMed
21.van Enk, RA, Thompson, KD. Use of a primary isolation medium for recovery of methicillin-resistant Staphylococcus aureus. J Clin Microbiol 1992; 30:504505.Google Scholar
22.Gorss, EB. Prospective, focused surveillance for oxacillin-resistant Staphylococcus aureus. In: Isenberg, IHD, ed. Clinical microbiology procedures handbook. Washington, DC: American Society for Microbiology; 1992: 11.15.111.15.2.Google Scholar
23.Singh, K, Gavin, PJ, Vescio, T, et al. Microbiologic surveillance using nasal cultures alone is sufficient for detection of methicillin-resistant Staphylococcus aureus isolates in neonates. J Clin Microbiol 2003; 41:27552757.Google Scholar
24.Sanford, MD, Widmer, AF, Bale, MJ, Jones, RN, Wenzel, RP. Efficient detection and long-term persistence of the carriage of methicillin-resistant Staphlyococcus aureus. Clin Infect Dis 1994; 19:11231128.Google Scholar
25.Papia, G, Louie, M, Tralla, A, Johnson, C, Collins, V, Simor, AE. Screening high-risk patients for methicillin-resistant Staphylococcus aureus on admission to the hospital: is it cost effective? Infect Control Hosp Epidemiol 1999; 20:473477.CrossRefGoogle Scholar
26.Shahin, R, Johnson, IL, Jamieson, F, McGeer, A, Tolkin, J, Ford-Jones, EL. Methicillin-resistant Staphylococcus aureus carriage in a child care center following a case of disease. Arch Pediatr Adolesc Med 1999; 153:864868.Google Scholar
27.Sa-Leau, R, Sanches, IS, Couto, I, Alves, CR, de Lencastre, H. Low prevalence of methicillin-resistant strains among Staphylococcus aureus colonizing young and healthy members of the community in Portugal. Microbial Drug Resistance 2001; 7:237245.CrossRefGoogle Scholar
28.Rihn, JA, Michaels, MG, Harner, CD. Community-acquired methicillin-resistant Staphylococcus aureus: an emerging problem in the athletic population. Am J Sports Med 2005; 33:19241929.Google Scholar
29.Flayhart, D, Hindler, JF, Bruckner, DA, et al. Multicenter evaluation of BBL CHROMagar MRSA medium for direct detection of methicillin-resistant Staphylococcus aureus from surveillance cultures of the anterior nares. J Clin Microbiol 2005; 43:55365540.Google Scholar
30.Warren, DK, Liao, RS, Merz, LR, Eveland, M, Dunne, WM Jr. Detection of methicillin-resistant Staphylococcus aureus directly from nasal swab specimens by a real-time PCR assay. J Clin Microbiol 2004; 42:55785581.Google Scholar
31.Check, W. Border patrol: MRSA admission screening. CAP Today 2005; 19. Available at: http://www.cap.org/apps/docs/cap_today/cover_stories/1005_MRSA_Admission_Screening.html. Accessed January 30, 2006.Google Scholar
32.Back, NA, Linnemann, CC Jr, Staneck, JL, Kotagal, UR. Control of methicillin-resistant Staphylococcus aureus in a neonatal intensive-care unit: use of intensive microbiologic surveillance and mupirocin. Infect Control Hosp Epidemiol 1996; 17:227231.Google Scholar
33.Struelens, MJ, Ronveaux, O, Jans, B, Mertens, R, the Groupement pour le Depistage, ‘Etude et la Prevention des Infections Hospitalieres. Methicillin-resistant Staphylococcus aureus epidemiology and control in Belgian hospitals, 1991 to 1995. Infect Control Hosp Epidemiol 1996; 17:503508.CrossRefGoogle ScholarPubMed
34.Karchmer, TB, Jernigan, JA, Durbin, BM, Simonton, BM, Farr, BM. Eradication of methicillin-resistant S. aureus (MRSA) colonization with different regimens. Program and Abstracts of the Ninth Annual Meeting of The Society for Healthcare Epidemiology of America- San Francisco, CA, April 18-20 1999. Abstract 65, p. 42.Google Scholar
35.Kotilainen, P, Routamaa, M, Peltonen, R, et al. Eradication of methicillin-resistant Staphylococcus aureus from a health center ward and associated nursing home. Arch Intern Med 2001; 161:859863.CrossRefGoogle Scholar
36.Kluytmans, J, Mouton, JW. IJzerman, EPF, et al. Reduction of surgical-site infections in cardiothoracic surgery by elimination of nasal carriage of Staphylococcus aureus. Infect Control Hosp Epidemiol 1996; 17:780785.Google Scholar
37.Kluytmans, JA, Manders, MJ, van Bommel, E, Verbrugh, H. Elimination of nasal carriage of Staphylococcus aureus in hemodialysis patients. Infect Control Hosp Epidemiol 1996; 17:793797.CrossRefGoogle ScholarPubMed
38.Weber, S, Herwaldt, LA, Mcnutt, LA, et al. An outbreak of Staphylococcus aureus in a pediatric cardiothoracic surgery unit. Infect Control Hosp Epidemiol 2002; 23:7781.Google Scholar
39.Doebbeling, BN, Breneman, DL, Neu, HC, et al. Elimination of Staphylococcus aureus nasal carriage in health care workers: analysis of six clinical trials with mupirocin calcium ointment. The Mupirocin Collaborative Study Group. Clin Infect Dis 1993; 17:466474.Google Scholar
40.Doebbeling, BN, Regan, DR, Pfaller, MA, Houston, AK, Hollis, RJ, Wenzel, RP. Long term efficacy of intranasal mupirocin ointment. A prospective cohort study of Staphylococcus aureus carriage. Arch Intern Med 1994; 154:15051508.Google Scholar
41.Harbarth, S, Dharan, S, Liassine, N, Herrault, P, Auckenthaler, R, Pittet, D. Randomized, placebo-controlled, double-blind trial to evaluate the efficacy of mupirocin for eradicating carriage of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 1999; 43:14121416.Google Scholar
42.Harbarth, S, Dharan, S, Liassine, N, Herrault, P, Auckenthaler, R, Pittet, D. Risk factors for persistent carriage of methicillin-resistant Staphylococcus aureus. Clin Infect Dis 2000; 31:13801385.Google Scholar
43.Walker, ES, Vasquez, JE, Dula, R, Bullock, H, Sarubbi, FA. Mupirocin-resistant, methicillin-resistant Staphylococcus aureus: does Mupirocin remain effective? Infect Control Hosp Epidemiol 2003; 24:342346.Google Scholar
44.Semret, M, Miller, MA. Topical mupirocin for eradication of MRSA colonization with mupirocin-resistant strains. Infect Control Hosp Epidemiol 2001; 229:578580.Google Scholar
45.Vasquez, JE, Walker, ES, Franzus, BW, Overbay, BK, Regan, DR, Sarubbi, FA. The epidemiology of mupirocin resistance among methicillin-resistant Staphylococcus aureus at a Veterans' Affairs hospital. Infect Control Hosp Epidemiol 2000; 21:459464.Google Scholar
46.Miller, MA, Dascal, A, Portnory, J, Medelson, J. Development of mupirocin resistance among methicillin-resistant Staphyloccus aureus after widespread use of nasal mupirocin ointment. Infect Control Hosp Epidemiol 1996; 17:811813.CrossRefGoogle Scholar
47.Netto dos Santos, K, de Souza, FL, Gontijo Filho, P. Emergence of high-level mupirocin resistance in methicillin-resistant Staphylococcus aureus isolated from Brazilian university hospitals. Infect Control Hosp Epidemiol 1996; 17:813816.Google Scholar
48.Vivoni, AM, Santos, KR, de-Oliveira, MP, et al. Mupirocin for controlling methicillin-resistant Staphylococcus aureus: lessons from a decade of use at a university hospital. Infect Control Hosp Epidemiol 2005; 26:662667.Google Scholar
49.Praz, SM, de Torrente, A, Zender, H, Schmied, E, Schleppy, CA, Genne, D. Toxic epidermal necrolysis after topical intranasal application of mupirocin. Infect Control Hosp Epidemiol 2003; 24:459460.Google Scholar
50.Loeb, M, Main, C, Walker-Dilks, C, Eady, A. Antimicrobial drugs for treating methicillin-resistant Staphylococcus aureus colonization. Cochrane Database Syst Rev 2003; 2:CD003340.Google Scholar
51.Blank, MK, Haas, L, Donahoe, M, Kramer, P, Muto, CA. Sustained effect in reducing methicillin-resistant Staphylococcus aureus (MRSA) hospital acquired infections (HAIs) using active MRSA surveillance cultures (MSC)—Three-year follow-up. Paper presented at: 15th Annual Society for Healthcare Epidemiology of America Conference, Los Angeles, California, 2005. Abstract 22.Google Scholar
52.Huang, SS, Yokoe, DS, Rego, VH, et al. Impact of ICU surveillance for MRSA on bacteremia. Paper presented at: 43rd Annual Meeting of The Infectious Diseases Society of America, San Francisco, CA, October 6-9 2005.Google Scholar
53.Thompson, R CI, Wenzel, R,. Epidemiology of nosocomial infections caused by methicillin-resistant Staphylococcus aureus. Ann Intern Med 1982;97:309317.Google Scholar
54.Stelfox, HT, Bates, DW, Redelmeier, DA. Safety of patients isolated for infection control. JAMA 2003; 290:18991905.Google Scholar
55.Centers for Disease Control and Prevention (CDC). Public health guidance for community-level preparedness and response to SARS. 2004. Available at: http://www.cdc.gov/ncidod/sars/guidance/index.htm. Accessed January 27, 2006.Google Scholar