Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-15T04:10:45.737Z Has data issue: false hasContentIssue false
  • English
  • Français

Methicillin-Resistant Staphylococcus aureus (MRSA): A Briefing for Acute Care Hospitals and Nursing Facilities

Published online by Cambridge University Press:  02 January 2015

John M. Boyce ,
Marguerite M. Jackson ,
Gina Pugliese ,
Murray D. Batt ,
David Fleming ,
Julia S. Garner ,
Alan I. Hartstein ,
Carol A. Kauffman ,
Mildred Simmons  and
Robert Weinstein
...Show all authors
John M. Boyce
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
Marguerite M. Jackson
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
Gina Pugliese*
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
Murray D. Batt
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
David Fleming
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
Julia S. Garner
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
Alan I. Hartstein
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
Carol A. Kauffman
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
Mildred Simmons
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
Robert Weinstein
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
Carol O'Boyle Williams
Affiliation:
Methicillin-Resistant Staphylococcus aureus Task Force, The American Hospital Association, Chicago, Illinois
*
American Hospital Association, 840 North Luke Shore Dr., Chicago, IL 60611
Get access Rights & Permissions [Opens in a new window]

Extract

The incidence of methicillin-resistant Staphylococcus aureus (MRSA) has increased in communities and in healthcare facilities in the United States since the mid-1970s. Although MRSA often is thought of as a nosocomial infection problem because it is encountered in facilities of all types and sizes, it also causes many community-acquired infections. Approaches to control of MRSA vary widely, and there is lack of agreement on the most appropriate measures to control MRSA in healthcare facilities. The wide variation in approaches is due, in part, to the lack of data establishing the efficacy of specific control measures. As a result, the approaches that have been advocated have resulted in confusing and often conflicting recommendations and control measures. In some settings, there also have been unreasonable barriers and administrative hurdles that delay or prevent the transfer of patients between acute care and nursing (extended care) facilities.

Type
Special Report
Information
Infection Control & Hospital Epidemiology , Volume 15 , Issue 2 , February 1994 , pp. 105 - 115
Copyright
Copyright © The Society for Healthcare Epidemiology of America 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Boyce, JM. Methicillin-resistant Staphylococcus aureus in hospitals and long-term care facilities: microbiology, epidemiology, and preventive measures. Infect Control Hosp Epidemiol 1992;13:725–737.Google Scholar
2. Haley, RW, Hightower, AW, Khabbaz, RR et al. The emergence of methicillin-resistant Staphylococcus aureus infections in United States hospitals. Possible role of the house staff-patient transfer circuit. Ann Intern Med 1982;97:297–308.CrossRefGoogle ScholarPubMed
3. Boyce, JM. Increasing prevalence of methicillin-resistant Staphylococcus aureus in the United States. Infect Control Hosp Epidemiol 1990;11:639–642.Google Scholar
4. Panlilio, AL, Culver, DH, Gaynes, RP, et al. Methicillin-resistant Staphylococcus aureus in U.S. Hospitals, 1975-1991. Infect Control Hosp Epidemiol 13:582–586.Google Scholar
5. McManus, AT, Mason, AD Jr, McManus, WF, Pruitt, BA Jr. What's in a name? Is methicillin-resistant Staphylococcus aureus just another S aureus when treated with vancomycin? Arch Surg 1989;124:1456–1459.CrossRefGoogle Scholar
6. Boyce, JM. Should we vigorously try to contain and control MRSA? Infect Control Hosp Epidemiol 1991; 12:46–54.Google Scholar
7. Bradley, SF; Terpenning, MS, Ramsey, MA, et al. Methicillin-resistant Staphylococcus aureus: colonization and infection in a long-term care facility. Ann Intern Med 1991;115:417–422.Google Scholar
8. Hackbarth, CJ, Chambers, HE Methicillin-resistant staphylococci: genetics and mechanisms of resistance. Antimicrob Agents Chemother 1989;33:991–994.CrossRefGoogle ScholarPubMed
9. Peacock, JE Jr, Moorman, DR Wenzel, RP, Mandeli, GL. Methicillin-resistant Staphylococcus aureus: microbiologic characteristics, antimicrobial susceptibilities, and assessment of virulence of an epidemic. Dis 1981;144:575–582.Google Scholar
10. Duckworth, GJ, Jordens, JZ. Adherence and survival properties of an epidemic methicillin-resistant strain of Staphylococcus aureus compared with those of methicillin-sensitive strains. J Med Microbiol 1990;32:195–200.Google Scholar
11. Jordens, JZ, Duckworth, GJ, Williams, RJ. Production of virulence factors by epidemic: methicillin-resistant Staphylococcus aureus in vitro. I Med Microbiol 1989;30:245–252.CrossRefGoogle ScholarPubMed
12. French, GL, Cheng, AF, Ling, JM, Mo, R Donnan, S. Hong Kong strains of methicillin-resistant and methicillin-sensitive Staphylococcus aureus have similar virulence. J Hosp Infect 1990;15:117–125.CrossRefGoogle ScholarPubMed
13. Jorgensen, JH. Mechanisms of methicillin resistance in Staphylo-coccus uureus and methods for laboratory detection. Infect Control Hosp Epidemiol 1991;12:14–19.CrossRefGoogle Scholar
14. Gerberding, JL, Miick, C, Liu, HH, Chambers, HE Comparison of conventional susceptibility tests with direct detection of penicillin-binding protein 2a in borderline oxacillin-resistant strains of Staphylococcus aureus. Antimicrob Agents Chemother 1991;35:2574–2579.Google Scholar
15. Archer, GL, Mayhall, CG. Comparison of epidemiological markers used in the investigation of an outbreak of methicillin-resistant Staphylococcus aureus infections. J Clin Microbiol 1983;18:395–399.CrossRefGoogle ScholarPubMed
16. Mulligan, ME, Arbeit, RD. Epidemiologic and clinical utility of typing systems for differentiating among strains of methicillin-resistant Staphylococcus aureus . Infect Control Hosp Epidemiol 1991;12:20–28.CrossRefGoogle ScholarPubMed
17. Thompson, RL, Cabezudo, I, Wenzel, RP. Epidemiology of nosocomial infections caused by methicillin-resistant Stabhvlococcus uureus. Ann Intern Med 1982;97:309–317.CrossRefGoogle Scholar
18. Muder, RR, Brennen, C, Wagener, MM, et al. Methicillin-resistant staphylococcal colonization and infection in a long-term care facility. Ann Intern Med 1991;114:107–112.CrossRefGoogle ScholarPubMed
19. Wenzel, RP, Nettleman, MD, Jones, RN, Pfaller, MA. Methicillin-resistant Staphylococcus uureus: implications for the 1990s and effective control measures. Am J Med 1991;91(suppl 3B):221S–227S.Google Scholar
20. Strausbaugh, LJ, Jacobson, C, Sewell, DL, Potter, S. Ward, TT. Methicillin-resistant Staphylococcus uureus in extendedcare facilities. Infect Control Hosb Epidemiol 1991;12:36–45 Google Scholar
21. Strausdaugh, LJ, Jacobson, C, Sewell, DL, Potter, S, Ward, 'IT Antimicrobial therapy for methicillin-resistant Staphylococcus aureus colonization in residents and staff of a Veterans Affairs nursing home care unit. Infect Control Hosp Epidemiol 1992;13:151–159.CrossRefGoogle Scholar