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Navigating the blood–brain barrier: enhancing blood culture practices in the neuro-ICU

Published online by Cambridge University Press:  27 January 2025

Maureen Metz ,
Katharine Colton  and
Jessica Seidelman Open the ORCID record for Jessica Seidelman [Opens in a new window]
Maureen Metz
Affiliation:
Departments of Neurology, Duke University, Durham, NC, USA
Katharine Colton
Affiliation:
Departments of Neurology, Duke University, Durham, NC, USA
Jessica Seidelman*
Affiliation:
Division of Infectious Diseases and International Health, Department of Medicine, Duke University School of Medicine, Duke University, Durham, NC, USA Duke Center for Antimicrobial Stewardship and Infection Prevention, Duke University Medical Center, Durham, NC, USA
*
Corresponding author: Jessica Seidelman; Email: jessica.seidelman@duke.edu
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Abstract

This study evaluates the implementation of a blood culture (BCx) algorithm in the neurology ICU (NICU) to reduce BCx event (BCE) rates. Results show a reduction in BCE rates, without increasing adverse outcomes. The findings support the feasibility of BCx algorithms for improving diagnostic stewardship in the specialized NICU population.

Type
Concise Communication
Information
Infection Control & Hospital Epidemiology , First View , pp. 1 - 3
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Copyright
© The Author(s), 2025. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

Fabre, V, Klein, E, Salinas, AB, et al. A diagnostic stewardship intervention to improve blood culture use among adult nonneutropenic inpatients: the DISTRIBUTE study. J Clin Microbiol 2020;58:e01053-20.CrossRefGoogle ScholarPubMed
Seidelman, JL, Moehring, R, Gettler, E, et al. Implementation of a diagnostic stewardship intervention to improve blood-culture utilization in 2 surgical ICUs: time for a blood-culture change. Infect Cont Hosp Ep 2024;45:452–458.CrossRefGoogle ScholarPubMed
Goyal, K, Garg, N, Bithal, P. Central fever: a challenging clinical entity in neurocritical care. J Neurocrit Care 2020;13:19–31.CrossRefGoogle Scholar
Hocker, SE, Tian, L, Li, GX, Steckelberg, J, Mandrekar, JN, Rabinstein, AA. Indicators of central fever in the neurologic intensive care unit. Jama Neurol 2013;70:1499–1504.Google ScholarPubMed
Badjatia, N. Hyperthermia and fever control in brain injury. Crit Care Med 2009;37:S250–S257.CrossRefGoogle ScholarPubMed
Gusdon, AM, Savarraj, JPJ, Shihabeddin, E, et al. Time course of peripheral leukocytosis and clinical outcomes after aneurysmal subarachnoid hemorrhage. Front Neurol 2021;12:694996.CrossRefGoogle ScholarPubMed
Theophanous, R, Ramos, J, Calland, AR, et al. Blood culture algorithm implementation in emergency department patients as a diagnostic stewardship intervention. Am J Infect Control 2024;52:985–991.CrossRefGoogle ScholarPubMed