Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-14T04:32:54.176Z Has data issue: false hasContentIssue false
  • English
  • Français

The Past, Present, and Future of Healthcare-Associated Infection Prevention in Pediatrics: Multidrug-Resistant Organisms

Published online by Cambridge University Press:  02 January 2015

Aaron M. Milstone ,
Kristina A. Bryant ,
W. Charles Huskins  and
Danielle M. Zerr
Aaron M. Milstone*
Affiliation:
Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
Kristina A. Bryant
Affiliation:
Department of Pediatrics, University of Louisville, Louisville, Kentucky
W. Charles Huskins
Affiliation:
College of Medicine, Mayo Clinic, Rochester, Minnesota
Danielle M. Zerr
Affiliation:
Department of Pediatrics, University of Washington, Seattle
*
John Hopkins University, Department of Pediatric Infectious Diseases, 200 North Wolfe Street, Rubenstein 3141, Baltimore, MD 21287 (amilstol@jhmi.edu)
Get access Rights & Permissions [Opens in a new window]

Abstract

Multidrug resistant organisms (MDROs) and healthcare-associated infections (HAIs) are associated with increased lengths of hospital stay, increased costs, and increased mortality. We explore the scope of MDRO HAIs in children, current MDRO HAI prevention practices and data to support these practices, and we propose research topics targeting MDRO HAI prevention in children.

Type
Supplement Article
Information
Infection Control & Hospital Epidemiology , Volume 31 , Issue S1: Papers from the Fifth Decennial International Conference on Healthcare-Associated Infections , November 2010 , pp. S18 - S21
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2010

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Siegel, JD, Krisher, KK, Levine, GL, et al.Prevalence of antimicrobial resistant bacteria in pediatric prevention networks intensive care units. In: Program and abstracts of the 39th Annual Meeting of the Infectious Diseases Society of America; October 25–28, 2001; San Francisco, CA. Abstract 311.Google Scholar
2.Grohskopf, LA, Sinkowitz-Cochran, RL, Garrett, DO, et al.A national point-prevalence survey of pediatric intensive care unit-acquired infections in the United States. J Pediatr 2002;140(4):432–438.CrossRefGoogle ScholarPubMed
3.Sohn, AH, Ostrowsky, BE, Sinkowitz-Cochran, RL, Quirk, SB, Jarvis, WR. Evaluation of a successful vancomycin-resistant enterococcus prevention intervention in a community of health care facilities. Am J Infect Control 2001;29(1):53–57.CrossRefGoogle Scholar
4.Raymond, J, Aujard, Y. Nosocomial infections in pediatric patients: a European, multicenter prospective study. European Study Group. Infect Control Hosp Epidemiol 2000;21(4):260–263.CrossRefGoogle ScholarPubMed
5.Milstone, AM, Carroll, KC, Ross, T, Shangraw, KA, Perl, TM. Community-associated methicillin-resistant Staphylococcus aureus strains in pediatric intensive care unit. Emerg Infect Dis 2010;16(4):647–655.Google Scholar
6.Milstone, AM, Maragakis, LL, Carroll, KC, Perl, TM. Targeted surveillance to identify children colonized with vancomycin-resistant enterococcus in the pediatric intensive care unit. Infect Control Hosp Epidemiol 2010;31(1):95–98.CrossRefGoogle ScholarPubMed
7.Gregory, ML, Eichenwald, EC, Puopolo, KM. Seven-year experience with a surveillance program to reduce methicillin-resistant Staphylococcus aureus colonization in a neonatal intensive care unit. Pediatrics 2009;123(5):e790–e796.Google Scholar
8.Lessa, FC, Edwards, JR, Fridkin, SK, Tenover, FC, Horan, TC, Gorwitz, RJ. Trends in incidence of late-onset methicillin-resistant Staphylococcus aureus infection in neonatal intensive care units: data from the National Nosocomial Infections Surveillance System, 1995–2004. Pediatr Infect Dis J 2009;28(7):577–581.CrossRefGoogle ScholarPubMed
9.Hidron, AI, Edwards, JR, Patel, J, et al.Antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006–2007. Infect Control Hosp Epidemiol 2008;29(11):996–1011.CrossRefGoogle Scholar
10.Milstone, AM, Song, X, Beers, C, Berkowitz, I, Carroll, KC, Perl, TM. Unrecognized burden of methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococcus carriage in the pediatric intensive care unit. Infect Control Hosp Epidemiol 2008;29(12):1174–1176.CrossRefGoogle ScholarPubMed
11.Gerber, SI, Jones, RC, Scott, MV, et al.Management of outbreaks of methicillin-resistant Staphylococcus aureus infection in the neonatal intensive care unit: a consensus statement. Infect Control Hosp Epidemiol 2006;27(2):139–145.CrossRefGoogle ScholarPubMed
12.Calfee, DP, Salgado, CD, Classen, D, et al.Strategies to prevent transmission of methicillin-resistant Staphylococcus aureus in acute care hospitals. Infect Control Hosp Epidemiol 2008;29(Suppl 1):S62–S80.CrossRefGoogle ScholarPubMed
13.Siegel, JD, Rhinehart, E, Jackson, M, Chiarello, L. Management of multidrug-resistant organisms in health care settings, 2006. Am J Infect Control 2007;35(10 Suppl 2):S165–S193.CrossRefGoogle ScholarPubMed
14.Jernigan, JA, Titus, MG, Groschel, DH, Getchell-White, S, Farr, BM. Effectiveness of contact isolation during a hospital outbreak of methicillin-resistant Staphylococcus aureus. Am J Epidemiol 1996;143(5):496–504.CrossRefGoogle ScholarPubMed
15.Haley, RW, Cushion, NB, Tenover, FC, et al.Eradication of endemic methicillin-resistant Staphylococcus aureus infections from a neonatal intensive care unit. J Infect Dis 1995;171(3):614–624.CrossRefGoogle ScholarPubMed
16.Milstone, AM, Budd, A, Shepard, JW, et al.Role of decolonization in a comprehensive strategy to reduce methicillin-resistant Staphylococcus aureus infections in the neonatal intensive care unit: an observational cohort study. Infect Control Hosp Epidemiol 2010;31(5):558–560.CrossRefGoogle Scholar
17.Kirkland, KB, Weinstein, JM. Adverse effects of contact isolation. Lancet 1999;354(9185):1177–1178.CrossRefGoogle ScholarPubMed